| 三七花颗粒的质量控制方法 |
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| 引用本文： | 冯军,刘布鸣. 三七花颗粒的质量控制方法[J]. 广西科学院学报, 2016, 32(4): 276-279. DOI: 10.13657/j.cnki.gxkxyxb.20161128.001 |
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| 作者姓名： | 冯军 刘布鸣 |
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| 作者单位： | 广西壮族自治区中医药研究院,广西中药质量标准研究重点实验室,广西南宁 530022 |
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| 基金项目： | 广西中药质量标准研究重点实验室系统性研究课题(桂中重系201310),广西科学研究与技术开发项目(重大专项计划;桂科重14124002-11)资助。 |
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| 摘 要： | 【目的】完善三七花颗粒制剂的质量控制标准。【方法】采用薄层色谱法对三七花颗粒进行定性鉴别,并用高效液相色谱法对颗粒中的人参皂苷Rb3进行定量测定。【结果】三七花颗粒供试品与对照品及药材在薄层色谱中相应的位置上,显现相同颜色的荧光斑点;人参皂苷Rb3在0.505~5.050μg成良好线性关系(r=0.999 9),平均回收率为101.25%,RSD为0.54%(n=6)。【结论】该方法简便、准确,可用于三七花颗粒质量的控制。
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| 关 键 词： | 高效液相色谱 薄层色谱 三七花颗粒 人参皂苷 Rb3 |
| 收稿时间： | 2016-06-10 |
Study on the Quality Control Method of Sanchi GranuLe |
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| FENG Jun and LIU Buming. Study on the Quality Control Method of Sanchi GranuLe[J]. Journal of Guangxi Academy of Sciences, 2016, 32(4): 276-279. DOI: 10.13657/j.cnki.gxkxyxb.20161128.001 |
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| Authors: | FENG Jun and LIU Buming |
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| Affiliation: | Guangxi Key Laboratory of Tradtitonal Chinese Medicine Quality Standards, Guangxi Institute of Traditional Medical and Pharmaceutical Sciences, Nanning, Guangxi, 530022, China and Guangxi Key Laboratory of Tradtitonal Chinese Medicine Quality Standards, Guangxi Institute of Traditional Medical and Pharmaceutical Sciences, Nanning, Guangxi, 530022, China |
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| Abstract: | [Objective]To perfect the quality control standard of sanchi granuLe.[Methods]The TLC method was used to identify the sanchi granuLe and the HPLC method was used for the determination of ginsenoside Rb3 in it.[Results]Each of the sanchi,sanchi granuLe and gin-senoside Rb3 had a similar fluorescent spot which performed the same colour and Rf in the TLC.The calibration curve of ginsenoside Rb3 showed a good linearity within 0.505~5.050μg,r=0.999 9.The average recovery was 101.25%,RSD was 0.54%(n=6).[Conclusion]The method was simple and accurate,it could be used for the quality control of Sanchi Gran-uLe. |
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| Keywords: | HPLC TLC sanchi granuLe ginsenoside Rb3 |
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