A new approach for the synthesis of some pyrazolo[5,1‐c]triazines and pyrazolo[1,5‐a]pyrimidines containing naphtofuran moiety |
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| Authors: | Abdou O Abdelhamid Shokry A Shokry Sayed M Tawfiek |
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| Affiliation: | 1. Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt;2. Science & Technology Center of Excellence, Slam 2nd., P.O. Box 3066, Egypt |
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| Abstract: | Naphtho2,1‐b]furan‐2‐yl)(8‐phenylpyrazolo5,1‐c]1,2,4]triazin‐3‐yl)methanone, (1,2,4]triazolo3,4‐c]1,2,4]triazin‐6‐yl)(naphtho2,1‐b]furan‐2‐yl)methanone, benzo4,5]imidazo2,1‐c]1,2,4]triazin‐3‐yl‐naphtho2,1‐b]furan‐2‐yl‐methanone, 5‐(naphtho2,1‐b]furan‐2‐yl)pyrazolo1,5‐a]pyrimidine, 7‐(naphtho2,1‐b]furan‐2‐yl)‐1,2,4]triazolo4,3‐a]pyrimidine, 2‐naphtho2,1‐b]furan‐2‐yl‐benzo4,5]imidazo1,2‐a]pyrimidine, pyridine, and pyrazole derivatives are synthesized from sodium salt of 5‐hydroxy‐1‐naphtho2,1‐b]furan‐2‐ylpropenone and various reagents. The newly synthesized compounds were elucidated by elemental analysis, spectral data, chemical transformation, and alternative synthetic route whenever possible. J. Heterocyclic Chem., (2012). |
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