老年人多动脉狭窄与心脑血管事件的相关性研究

目的 研究老年人动脉粥样硬化性血管狭窄数目与心脑血管事件之间的相互关系.方法 回顾性分析在北京协和医院特需门诊固定查体年龄大于或等于60岁的老年人(中位年龄83岁),完成颈动脉、下肢动脉及肾动脉多普勒超声检查者共163例,记录一般情况、心脑血管事件及其主要危险因素,以及外周血管超声检查结果.结果 随着颈、肾及下肢动脉血管狭窄部位的增加,年龄(F=13.413,P＜0.001)、高血压、高脂血症、服用他汀类药物(x2=24.961、13.592、16.207,均P＜0.001)的比例均明显升高,存在显著差异.血管狭窄数目与心脑血管事件之间显著相关(x2=15.258,P＜0.001).症状性外周动脉硬化闭塞症可以增加心脑血管事件的发生率.结论 多部位检出动脉血管狭窄与心脑血管事件之间显著相关,多普勒超声是检出更高危患者的一个有效手段.

The relationship between number of peripheral artery stenosis and cardio-cerebrovascular events in the elderly

Objective To investigate the association between the number of periphery artery atherosclerotic stenosis and cardio-cerebrovascular events in elderly people.Methods Totally 163 subjects aged 60 years and over (median age 83 years) in special outpatient service of PUMC Hospital were retrospectively reviewed and underwent Doppler ultrasound of carotid,lower extremity,and renal artery.General conditions,cardio-cerebrovascular events,risk factors and results of periphery artery ultrasound were assessed.Results Age (F =13.413,P ＜ 0.001 ),hypertension,hyperlipidemia and the statin users(x2 =24.961、13.592、16.207,all P＜0.001) significantly enhanced along with increasing number of peripheral artery stenosis (P＜0.001).The more the peripheral arteries stenosis,the more cardio-cerebrovascular events occurred (x2 =15.258,P ＜ 0.001).Symptomatic peripheral artery obstructive disease increased the prevalence of cardio-cerebrovascular events.Conclusions Multiple periphery artery atherosclerotic stenosis is associated with cardiocerebrouascular events and Doppler ultrasound is effective to detect high-risk patients.