老年男性高血压患者脉压指数特征的分析

目的分析老年男性高血压患者脉压指数特征及其对心脑血管事件危险性的预测价值。方法选择265例老年男性高血压患者进行动态血压监测,按脉压指数水平分层:≤0.400(103例),0.401～0.500(124例),≥0.501(38例),分析高血压患者昼夜及不同脉压指数的动态血压特征及心脑血管事件危险性。结果高血压患者夜间脉压较昼间明显降低(P<0.01);脉压指数昼夜变化幅度较小,差异无统计学意义(P>0.05)。随脉压指数增加,高血压患者平均收缩压(24 h、昼间、夜间)、平均脉压(24 h、昼间、夜间)、收缩压最高值、收缩压变异性(24 h、昼间)、夜间收缩压负荷值明显升高;而平均舒张压(24 h、昼间、夜间)、舒张压最低值、昼间舒张压负荷值、夜间血压下降率均明显下降(P<0.01)。随脉压指数增加,心脑血管事件发生率增高(P<0.01)。结论脉压指数较脉压更有利于对患者动脉硬化做出准确评估,且对老年男性高血压患者心脑血管事件危险性有一定预测价值。

Analysis of the characteristics of pulse pressure index in elderly men with hypertension

Objective To analyze the characteristics of pulse pressure index(PPI) and its value in predicting the risk for cerebral and cardiac vascular events in old males with hypertension. Meth-ods The 24-hours ambulatory blood pressure monitoring was performed in a total of 265 elderly men with essential hypertension(EH). The patients were classified into 3 groups based on the lev-el of PPI.PPI≤0.400(103) ,0. 401-0. 500(124) ,and≥0.501(38). Results There was significant difference in PP between day-time and night-time in hypertensive patients. The change of PPI was less than that of PP. With the increase in PPI, SBP(24 h, day-time, night-time), PP(24 h, day-time, night-time), the load of SBP(night-time), systolic blood pressure variation(BPV, 24 h, day-time) were raised significantly (P<0.01); while DBP(24 h, day-time, night-time), nocturnal de-cline in BP and the load of DBP(day-time) declined with the decrease in PPI (P<0.01). High PPI would increase the incidence of cardiac-cerebral vascular events (P < 0.01). Conclusion PPI is a useful parameter in clinical evaluation of arteriosclerosis. It may also have prognostic value for cardiac-cerebral vascular events in elderly men with EH.