| 局部光动力学疗法并区域适形调强放射同步中药治疗肿瘤的量效分析 |
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| 引用本文： | 王义善,王钦文,贾喜凤,曲震,生梦飞,盛娜.局部光动力学疗法并区域适形调强放射同步中药治疗肿瘤的量效分析[J].中华中医药杂志,2008,23(12):1085-1089. |
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| 作者姓名： | 王义善 王钦文 贾喜凤 曲震 生梦飞 盛娜 |
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| 作者单位： | 山东烟台解放军第107医院国家中西医结合肿瘤治疗重点专科,烟台264002 |
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| 基金项目： | 全军科技攻关计划基金资助项目 |
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| 摘 要： | 目的:探讨局部光动力学疗法(photodynamic therapy,PDT)并区域适形调强(IMCRT)治疗的剂量效应.通过中药的辅助整合为中晚期肿瘤患者提供不同策略有效综合治疗的依据.方法:对手术失败或无手术适应症的空腔或浅表肿瘤患者,采用局部与区域的综合治疗手段,观察分析20min、30min、200J/cm2、300J/cm2、1次、3次光化物理疗法(PCT/PDT)不同时间、剂量、分次(TDF)与IMCRT和同步中医药治疗的量效关系.结果:PDT物理疗法与IMCRT和同步中医药治疗,随着TDF的变化有显著统计意义,PDT对中晚期肿瘤特别是空腔脏器患者,减轻症状提高生活质量是肯定的,对梗阻型、放化疗失败的中晚期肿瘤患者有较高的姑息治疗价值.结论:采用PDT、IMCRT与中药不同策略的整合治疗,通过TDF的优化同步中医药的辅助方案,创伤性小、副作用少,可达到减毒增效带瘤生存的目的,使中晚期肿瘤患者"变不治为可治".
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| 关 键 词： | 光化疗法 适形调强 中药/狼毒 量效分析 临床研究 |
Clinical dose effect analysis on photodynamic therapy combined with IMCRT and TCM for cancer |
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| WANG Yi-shan,WANG Qin-wen,JIA Xi-feng,QU Zhen,SHENG Meng-fei,SHENG Na.Clinical dose effect analysis on photodynamic therapy combined with IMCRT and TCM for cancer[J].China Journal of Traditional Chinese Medicine and Pharmacy,2008,23(12):1085-1089. |
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| Authors: | WANG Yi-shan WANG Qin-wen JIA Xi-feng QU Zhen SHENG Meng-fei SHENG Na |
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| Affiliation: | WANG Yi-shan,WANG Qin-wen,JIA Xi-feng,QU Zhen,SHENG Meng-fei,SHENG Na(National Key Department of Combined Treatment of Traditional Chinese , Western Medicine for Tumor,Chinese PLA 107 Hospital,Yantai 264002,China) |
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| Abstract: | Objective:To investigate the dose effect of PDT(photodynamic therapy)combined with regional IMCRT(intensity modulated comformed radiotherapy)and TCM on advanced cancer.Methods:Patients with operation failure or inoperable carcinomatous patients,received PDT and IMCRT or TCM.They were divided randomly into different groups according to different treatment course,different dose and different curative time of PCT/PDT.Results:The chemical treatment of PDT combined with IMCRT and TCM for advanced cancer especial... |
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| Keywords: | Photodynamic chemical therapy Intensity modulated comformed radiotherapy Euphorbiae scherianae Dose effect analysis Clinical research |
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