| 方酸菁荧光探针的应用研究进展 |
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| 引用本文： | 石伟宁,徐勇前,孙世国,李红娟.方酸菁荧光探针的应用研究进展[J].应用化学,2017,34(12):1433-1449. |
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| 作者姓名： | 石伟宁 徐勇前 孙世国 李红娟 |
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| 作者单位： | 西北农林科技大学化学与药学院 陕西省天然产物与化学生物学重点实验室 陕西 杨凌 712100 |
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| 基金项目： | 国家自然科学基金资助项目(21676218,21476185,21472016,21272030) |
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| 摘 要： | 功能性方酸菁染料具有独特的D-A-D共轭结构,其在可见光和近红外区域有强烈的吸收和荧光发射。方酸菁染料作为近红外荧光探针母体被应用于蛋白质、氨基酸、一些生物小分子、环境污染物及金属离子等的检测。本文结合课题组近几年工作综述了方酸菁染料在蛋白质、氨基酸、生物小分子、阳离子和其它物质检测方面的应用。
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| 关 键 词： | 方酸菁染料 近红外荧光探针 生物检测 聚集-解聚 |
| 收稿时间： | 2017-09-11 |
Research Progress on Application of Fluorescent Sensors Based on Squaraine Dyes |
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| SHI Weining,XU Yongqian,SUN Shiguo,LI Hongjuan.Research Progress on Application of Fluorescent Sensors Based on Squaraine Dyes[J].Chinese Journal of Applied Chemistry,2017,34(12):1433-1449. |
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| Authors: | SHI Weining XU Yongqian SUN Shiguo LI Hongjuan |
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| Affiliation: | Shaanxi Key Laboratory of Natural Products & Chemical Biology,College of Chemistry &Pharmacy,Northwest A&F University,Yangling,Shaanxi 712100,China |
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| Abstract: | Due to the unique D-A-D conjugate structure, squaraine dyes possess strong absorption and fluorescence emission in the visible and near infrared regions. As the fluorophore of near infrared fluorescent probes, it has been applied for detection of proteins, amino acids and small biological molecules in vivo, environmental pollutants and so on. In this paper, we reviewed the application of squaraine dyes in the detection of proteins, amino acids, small molecules, cations and other substances according to the work of our group in these years. |
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| Keywords: | squaraine dye near infrared fluorescence probes bioassay aggregation-deaggregation |
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