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荞麦多糖对小鼠实验性肝损伤的保护作用
引用本文:曾靖,张黎明,江丽霞,申蕊,徐惠荣,叶和杨.荞麦多糖对小鼠实验性肝损伤的保护作用[J].中药药理与临床,2005,21(5):29-30.
作者姓名:曾靖  张黎明  江丽霞  申蕊  徐惠荣  叶和杨
作者单位:1. 赣南医学院,药理教研室,赣州,341000
2. 天津科技大学生物工程学院植化教研室,天津,300222
3. 赣南医学院,附属医院检验科
摘    要:目的:研究荞麦多糖对小鼠实验性肝损伤的保护作用.方法:采用四氯化碳(CCl4)、硫代乙酰胺(TAA)、扑热息痛(AAP)致小鼠急性肝损伤模型,测定小鼠血清SGPT活性.结果:荞麦多糖溶液对四氯化碳、扑热息痛所致小鼠实验性肝损伤有明显保护作用,但对硫代乙酰胺所致小鼠实验性肝损伤无明显的保护作用.结论:荞麦多糖有保肝作用.

关 键 词:荞麦多糖  保肝

Protective effects of Fagopyrum esculentum polysaccharide on experimental liver injuries in mice
Zeng Jing, Zhang Liming, Jiang Lixia.Protective effects of Fagopyrum esculentum polysaccharide on experimental liver injuries in mice[J].Pharmacology and Clinics of Chinese Materia Medica,2005,21(5):29-30.
Authors:Zeng Jing  Zhang Liming  Jiang Lixia
Affiliation:Department of Pharmacology, Gannan Medical college, Ganzhou 341000
Abstract:Objective: To study the protective effect of Fagopyrum esculentum polysaccharide on experimental liver injuries.Methods: The activity of serum SGPT were measured in the model mice of liver injury induced by carbon tetrachloride(CCl_4),acetaminophen(AAP) and thioacetamide(TAA).Result: The serum SGPT activity was significantly lowered in the model mice of liver injure induced by CCl_4 and AAP after Fagopyrum esculentum polysaccharide was given orally.Conclusion: Fagopyrum esculentum polysaccharide exhibited protective effect on experimental liver injuries.
Keywords:Fagopyrum esculentum polysaccharide  liver injury  SGPT
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