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恶性淋巴细胞增殖性疾病外周血自然杀伤细胞计数及活性变化的研究
引用本文:孟秀香,林慧娴,宋鉴清,刘基.恶性淋巴细胞增殖性疾病外周血自然杀伤细胞计数及活性变化的研究[J].大连医科大学学报,1995(1).
作者姓名:孟秀香  林慧娴  宋鉴清  刘基
作者单位:Division of Clinical Laboratory,Department of Hematology,Dalian Medical University
摘    要:本文对20例正常人及30例恶性淋巴细胞增殖性疾病(MLPD)病人进行NKC计数及活性的研究,结果表明:后者的自然杀伤细胞(NKC)活性显著低于前者而计数结果却显著高于前者,并发现完全缓解期病人的NK活性显著高于未缓解及部分缓解者,处于化疗及放疗中的病人的NK活性显著低于其它病期,对MLPD患者的NKC数量及活性进行相关性分析的结果表明二者无相关性(P>0.05),本文就NKC计数及活性的变化及意义进行了探讨。

关 键 词:恶性淋巴细胞增殖性疾病(MLPD)  自然杀伤细胞(NKC)计数  NK活性  淋巴瘤  淋巴细胞白血病

Changes of nature killer cell count and activity in malignant lymphoid proliferative diseases
Meng Xiuxiang,et al.Changes of nature killer cell count and activity in malignant lymphoid proliferative diseases[J].Journal of Dalian Medical University,1995(1).
Authors:Meng Xiuxiang  
Abstract:Nature killer cell count anb activity were studied in 20 normal subjects and 30 patients with malignant lymphoid diseases.The results showed that significantly lower activity and higher count in nature killer cell were found in patients than that in normal subjects.It was also found that the nature killer cell activity in complete remission patients was significantly higher than that in non-remission and partial remission patients, and the nature killer cell activity during chemotherapy or radiotherapy was significantly lower than that in any other stages of the diseases. No correlation was found between nature killer cell count and activity in malignant lymphoid proliferative diseases.The significance of changes in nature killer cell count and activity was also discussed.
Keywords:Malignant lymphoid proliferative disease(MLPD)  nature killer cell count  nature killer activity  lymphoma  lymphocytic leukemia
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