慢性阻塞性肺疾病患者BODE指数与焦虑抑郁症状的相关性研究

目的探讨慢性阻塞性肺病(慢阻肺)患者的BODE指数与焦虑抑郁症状的相关关系,为今后慢阻肺患者的负性情绪干预提供依据。方法选取2011年1月至2014年1月间于我院接受治疗的慢阻肺患者186例作为研究对象,收集患者的一般性资料,并同时测量每位患者6分钟步行距离(6MWD);采用英国医学研究委员会呼吸困难量表(MRC dyspned scale)记录气促分级并评分;测量肺功能;测量患者的身高、体重,进而进行BODE多维分级系统评分,之后再采用Hamilton抑郁量表(HAMD)以及焦虑量表(HAMA)测量患者的焦虑抑郁情绪,分析相关性。结果 Hamilton抑郁量表(HAMD)以及焦虑量表(HAMA)测量结果显示186例慢阻肺患者中有77例出现焦虑情绪,而有86例出现抑郁情绪,单因素分析显示,BODE总分、呼吸困难指数、6MWD均是导致患者出现负性情绪的危险因素,其与焦虑的相关系数分别为0.51、0.55、-0.48,而与抑郁的相关系数分别为0.53、0.55、-0.51。结论慢阻肺患者存在明显的焦虑、抑郁负性情绪,在临床干预中,BODE指数总分及其分项的6MWD、呼吸困难指数均可以作为判断慢阻肺患者焦虑抑郁的重要指标,对患者的情绪干预提供有效参考。

Correlation between BODE index of patients with chronic obstructive pulmonary disease and anxiety depres-sion symptoms

Objective To explore the correlation between the BODE index of patients with chronic obstruc-tive pulmonary disease ( COPD) and anxiety depression symptoms. Methods 186 COPD patients from January 2014 and January 2011 in our hospital were selected as the research objects, and their general information were collected. Their 6-minute walking distance (6 MWDS) was measured, The shortness of breath was scored by the medical re-search council dyspnea scale ( MRC dyspnea scale) . Besides, their lung function, height, and weight were recorded to score BODE multidimensional classification system. It used the Hamilton depression rating scale ( HAMD) and anxiety scale ( HAMA) to measure their anxiety depression. Results The Hamilton depression scale ( HAMD) and anxiety scale ( HAMA) measurement results showed that there were 77 patients with anxiety and 86 patients with de-pression. Single factor analysis showed that BODE scores, dyspnea index, and 6 MWDS were the risk factors causing patients with negative emotions, and its correlation with anxiety was 0. 51, 0. 55, and 0. 48, and 0. 53, 0. 55, and 0. 51 with depression, respectively. Conclusion There exists obvious anxiety and depression in COPD patients. In the actual clinical treatment, BODE index scores, 6-minute walking distance and dyspnea index can be used as sig-nificant predictors for COPD patients with anxiety and depression.