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中药量效关系的研究进展
引用本文:朱春胜,聂安政,王笑,张冰.中药量效关系的研究进展[J].中草药,2019,50(7):1708-1712.
作者姓名:朱春胜  聂安政  王笑  张冰
作者单位:郑州大学第一附属医院, 河南 郑州 450000,郑州大学第一附属医院, 河南 郑州 450000,北京中医药大学, 北京 100102,北京中医药大学, 北京 100102
基金项目:国家自然科学基金资助项目(81673618);北京市自然科学基金项目(7162117)
摘    要:量效关系是确定中药临床用药剂量的依据,是保障中药临床用药安全、有效的关键。对近10年来有关中药量效关系的研究思路、研究现状、研究瓶颈等相关文献进行梳理、总结,并建议将谱效关系理论引入中药量效关系研究中,为推动中药量效关系进一步深入研究提供参考和借鉴。

关 键 词:中药  量效关系  临床用药剂量  效应物质  谱效关系
收稿时间:2018/12/16 0:00:00

Research progress on dose-effect relationship of Chinese materia medica
ZHU Chun-sheng,NIE An-zheng,WANG Xiao and ZHANG Bing.Research progress on dose-effect relationship of Chinese materia medica[J].Chinese Traditional and Herbal Drugs,2019,50(7):1708-1712.
Authors:ZHU Chun-sheng  NIE An-zheng  WANG Xiao and ZHANG Bing
Affiliation:The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, China,The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, China,Beijing University of Chinese Medicine, Beijing 100102, China and Beijing University of Chinese Medicine, Beijing 100102, China
Abstract:The dose-effect relationship of Chinese materia medica (CMM) is the basis to determine the clinical dosage, as well as the key to ensure the safety and effectiveness in clinic. In this paper, the author reviews and summarizes the research ideas, research status, and research bottlenecks related to the dose-effect relationship of CMM in the past 10 years. It is suggested to introduce the theory of spectrum-effect relationship into the study of dose-effect relationship, so as to provide reference for further research on the dose-effect relationship of CMM.
Keywords:Chinese materia medica  dose-effect relationship  clinical dosage  effective substa  spectrum-effect relationship
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