Basal and gonadotropin releasing hormone-stimulated gonadotropin secretion in patients with chronic uremia |
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| Authors: | K Rudolf S Kunkel H Rudolf D Falkenhagen M Rüting |
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| Affiliation: | Klinik für Gyn?kologie und Geburtshilfe, Bereichs Medizin, Wilhelm-Pieck-Universit?t Rostock. |
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| Abstract: | In 11 patients with chronic uremia both the basal and stimulated levels of LH and FSH in serum were determined by RIA. After renal transplantation the investigations were repeated in 2 cases. The basal levels of LH were unphysiologically increased whereas FSH was found in the normal range. The stimulation of LH by GnRH was adequate in 6 patients and in 5 there was no response. As a result of renal transplantation there was a drop of LH in serum. It is supposed that the unphysiological increase of LH in patients with chronic uremia is the cause for the disturbances of the menstrual cycle. |
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