| 羧基官能团化的苹果酰亚胺衍生物的合成 |
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| 引用本文： | 张萍,贾会珍,孙耀冉,李媛. 羧基官能团化的苹果酰亚胺衍生物的合成[J]. 化学试剂, 2006, 28(11): 651-652,656 |
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| 作者姓名： | 张萍 贾会珍 孙耀冉 李媛 |
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| 作者单位： | 河北师范大学,化学学院,河北,石家庄,050016;河北师范大学,化学学院,河北,石家庄,050016;石家庄学院,化学系,河北,石家庄,050801 |
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| 摘 要： | 用氨基酸与苹果酸酐直接反应,合成了两个含羧基官能团的苹果酰亚胺,为氨基酸氮端的保护以及含羧基官能团的酰亚胺类化合物的合成提供了一种直接、简便的新方法。
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| 关 键 词： | 苹果酰亚胺 酸酐 氨基酸 |
| 文章编号： | 0258-3283（2006）11-0651-02 |
| 收稿时间： | 2006-04-15 |
| 修稿时间： | 2006-04-15 |
Synthesis of carboxyl functionalized imide derivatives of maleimide |
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| ZHANG Ping,JIA Hui-zhen,SUN Yao-ran,LI Yuan. Synthesis of carboxyl functionalized imide derivatives of maleimide[J]. Chemical Reagents, 2006, 28(11): 651-652,656 |
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| Authors: | ZHANG Ping JIA Hui-zhen SUN Yao-ran LI Yuan |
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| Affiliation: | 1. College of Chemistry, Hebei Normal University, Shijiazhuang 050016, China;2, Department of Chemistry, ShijiazhuangCollege, Shijiazhuang 050801, China |
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| Abstract: | 2 New carbonyl functionalized imide derivatives of maleimide were synthesized by the direct reaction of amino acids with maleic anhydride.Their structures were characterized by elementary analysis,IR, ~1HNMR , ~ 13 CNMR ,and MS.A new simple and direct method for protecting the nitrogen terminals of amino acids and synthesis of imide derivatives was provided. |
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| Keywords: | maleimide anhydride amino acid |
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