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黄骅市高碘地区甲状腺功能亢进患者颈动脉粥样硬化相关性的研究
引用本文:丁长霞,王艳芳,刘存杰,赵海云,李冲,张秀丽,韩红伟. 黄骅市高碘地区甲状腺功能亢进患者颈动脉粥样硬化相关性的研究[J]. 现代中西医结合杂志, 2013, 22(13): 1381-1382
作者姓名:丁长霞  王艳芳  刘存杰  赵海云  李冲  张秀丽  韩红伟
作者单位:丁长霞 (河北省黄骅市人民医院,河北黄骅,061100); 王艳芳 (河北省黄骅市人民医院,河北黄骅,061100); 刘存杰 (河北省冀东监狱,河北唐山,063305); 赵海云 (河北省黄骅市人民医院,河北黄骅,061100); 李冲 (河北省黄骅市人民医院,河北黄骅,061100); 张秀丽(河北省黄骅市人民医院,河北黄骅,061100);韩红伟(河北省黄骅市人口和计划生育局,河北黄骅,061100);
基金项目:河北省科学技术研究与发展资金项目(项目编号:11276167)
摘    要:目的探讨黄骅市高碘地区甲状腺功能亢进(甲亢)患者颈动脉粥样硬化病变的特点,前瞻性探讨其对缺血性脑卒中发病的影响。方法选择甲亢患者120例(甲亢组)与健康志愿者100例(对照组)进行血液生化及颈动脉彩超检查,观察2组血糖、糖化血红蛋白、血脂指标以及颈动脉斑块形成、血管狭窄情况。结果甲亢组血FT3、FT4、血糖、糖化血红蛋白均高于对照组,总胆固醇、三酰甘油、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇均低于对照组;甲亢组颈动脉IMT、斑块数和狭窄数明显高于对照组。结论甲亢影响血糖、血脂代谢,促进颈动脉内膜增厚及斑块形成,是缺血性脑卒中的独立危险因素。

关 键 词:甲亢  颈动脉硬化  血糖  血脂  彩色多普勒超声

Correlation of hyperthyroidism and carotid artherosclerosis in high iodine area of Huanghua City
Abstract:Objective It is to investigate the characteristics of carotid atherosclerotic lesions of patients with hyperthyroidism in high iodine area of Huanghua City,and to explore its influence on cerebral arterial thrombosis prospectively.Methods 120 patients with hyperthyroidism(hyperthyroidism group) and 100 cases of healthy volunteers(control group) were investigated,the changes of blood sugar,glycated hemoglobin,blood fat index and carotid plaques,hemadostenosis were observed respectively.Results The levels of FT3,FT4,blood sugar,HBAlc in hyperthyroidism group were higher than those of the control group;TC,TG,HDL-C,LDL-C were lower than those of the control group;IMT,numbers of plaque and hemadostenosis of carotid artery were significantly higher than of control group.Conclusion Hyperthyroidism can influence the metabolism of blood sugar,blood fat,promote thickening of carotid endarterectomy and plaque formation,it is a independent risk factor of cerebral arterial thrombosis.
Keywords:hyperthyroidism  carotid atherosclerosis  blood sugar  blood fat  color doppler ultrasound
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