| 板蓝根醇提部位化学成分研究 |
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| 引用本文： | 孙东东,李祥,陈建伟,何立巍. 板蓝根醇提部位化学成分研究[J]. 中国药房, 2007, 18(30): 2325-2326 |
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| 作者姓名： | 孙东东 李祥 陈建伟 何立巍 |
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| 作者单位： | 南京中医药大学,南京市,210046 |
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| 摘 要： | 目的:从板蓝根中分离化学成分。方法:板蓝根95%乙醇提取物经硅胶吸附,不同溶剂洗脱部分经硅胶柱层析反复分离纯化,测定所得化合物的理化常数和波谱数据,鉴定其化学结构。结果:从氯仿部位分得5个化合物,从正丁醇部位分得1个化合物,分别鉴定为:胆甾醇(Ⅰ)、靛蓝(Ⅱ)、靛玉红(Ⅲ)、对羟基苯甲醛(Ⅳ)、水杨酸(Ⅴ)、落叶松脂素-4,4′-2-O-β-D-二葡萄糖苷(Ⅵ)。结论:化合物Ⅰ、Ⅳ为首次从板蓝根药材中分离,具有一定的参考价值。
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| 关 键 词： | 板蓝根 化学成分 分离 鉴定 |
| 文章编号： | 1001-0408（2007）30-2325-02 |
| 收稿时间： | 2007-03-10 |
| 修稿时间： | 2007-06-20 |
Study on Chemical Constituents Extracted with Ethanol from Radix Isatidis |
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| SUN Dongdong,LI Xiang,CHEN Jianwei,HE Liwei. Study on Chemical Constituents Extracted with Ethanol from Radix Isatidis[J]. China Pharmacy, 2007, 18(30): 2325-2326 |
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| Authors: | SUN Dongdong LI Xiang CHEN Jianwei HE Liwei |
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| Affiliation: | Nanjing University of Traditional Chinese Medicine, Nanjing 210046, China |
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| Abstract: | OBJECTIVE:To isolate the chemical constituents from Radix isatidis.METHODS:The 95% ethanol extract of Radix Isatidis underwent adsorption by silica gel,and the portion eluted by different solvents was isolated and purified on silica gel column repeatedly.The physico-chemical constants and spectral data of the obtained compounds were determined and their chemical structure was identified.RESULTS:6 compounds were separated from chloroform and n-Butanol parts of Radix Isatidis and identified as:cholesterol(Ⅰ),indigotin(Ⅱ),indirubin(Ⅲ),p-Hydroxybenzaldehyde(Ⅳ),salicylic acid(Ⅴ),lariciresinol-4,4'-2-O-β-D-glucopyranoside(Ⅵ),respectively.CONCLUSION:For the first time,compound(Ⅰ)and compound(Ⅳ)were isolated from Radix Isatidis,this finding serves as reference. |
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| Keywords: | Radix Isatidis Chemical constituents Isolation Identification |
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