| 2型糖尿病患者心率变异性与血清P-选择素水平的相关性 |
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| 引用本文： | 颜红训,张卫民.2型糖尿病患者心率变异性与血清P-选择素水平的相关性[J].中国热带医学,2011,11(7):901-901,907. |
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| 作者姓名： | 颜红训 张卫民 |
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| 作者单位： | 1. 解放军第158医院心内科,广西柳州,545001
2. 解放军第421医院内一科,广东广州,515101 |
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| 摘 要： | 目的探讨2型老年糖尿病患者心率变异性（Heart rate vanability，HRV）与血清P-选择素变化的相关性。方法选择68-例老年糖尿病患者行24h动态心电图检查，测定HRV，包括所有窦性心搏R—R（NN）间期的标准差（SDNN）、全程记录中每5minNN间期平均值的标准差（SDANN）、相邻NN间期差值的均方根（rMSSD），ELISA法检测其血清P－选择素水平，并与40例老年健康对照组比较。结果糖尿病组HRV参数显著低于对照组（p〈0．05），而血清P－选择素水平较对照组显著升高（P〈0．05），且HRV与血清P－选择素水平具有显著的负相关性（r＝－0．27，r＝00．17，r＝－0．26。P〈0．05）。结论糖尿病患者心脏自主神经功能的改变和血清P－选择素水平的变化具有相关性。
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| 关 键 词： | 2型糖尿病 心率变异性 血清 P-选择素 |
Relationship between heart rate variability and serum P-selectin in senile type-2 diabetes mellitus patients |
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| YAN Hong-xun..Relationship between heart rate variability and serum P-selectin in senile type-2 diabetes mellitus patients[J].China Tropical Medicine,2011,11(7):901-901,907. |
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| Authors: | YAN Hong-xun |
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| Affiliation: | YAN Hong-xun.(Department of Cardiology of NO 158 hospital of PLA,Liuzhou 531001,China) |
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| Abstract: | Objective To observe the relationship between heart rate variability(HRV) and serum P-selectin in type 2 diabetic aged patients(2-DM).Methods The serum P-selectin and heart rate variability(HRV) of 68 aged patients with 2-DM were examined respectively.HRV was assessed by calculating the indices based on statistical operation on RR intervals from 24-hour Hoher recording.including:standard deviation of normal to normal RR intervals(SDNN),standard deviation of 5 minute mean RR intervals(SDANN) and square root ... |
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| Keywords: | type-2 diabetes mellitus heart rate variability P-selectin |
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