| 茵陈蒿汤对免疫小鼠ABO血型抗体产生的抑制作用研究 |
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| 引用本文： | 周华友,于艳涛,张文,张健媛,杨贺才,刘持翔,王淑红,石文. 茵陈蒿汤对免疫小鼠ABO血型抗体产生的抑制作用研究[J]. 中国免疫学杂志, 2011, 27(7): 607-610. DOI: 10.3969/j.issn.1000-484X.2011.07.007 |
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| 作者姓名： | 周华友 于艳涛 张文 张健媛 杨贺才 刘持翔 王淑红 石文 |
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| 作者单位： | 广东省中医院,广州,510120 |
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| 基金项目： | 广东省建设中医药强省基金资助项目，广州中医药大学创新基金资助项目 |
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| 摘 要： | 目的:研究茵陈蒿汤对ABO血型抗体分泌细胞的抑制作用。方法:以人A型红细胞免疫BALB/c小鼠,通过间接抗人球蛋白试验,吸收放散试验和IgG型抗-A效价的检测等观察A型红细胞免疫组和茵陈蒿汤治疗组中BALB/c小鼠体内IgG型抗-A抗体的水平变化。结果:对照组BALB/c小鼠均未捡测出IgG型抗-A抗体,免疫组BALB/c小鼠均产生IgG型抗-A抗体,茵陈蒿汤治疗组中有5只没有检测到IgG型抗-A抗体,11只BALB/c小鼠产生了IgG型抗-A抗体。间接抗人球蛋白试验,吸收放散试验和IgG型抗-A效价的检测结果显示免疫组和茵陈蒿汤治疗组IgG型抗-A水平均高于对照组(P<0.05),茵陈蒿汤治疗组抗-A水平低于免疫组(P<0.05),茵陈蒿汤治疗组抗-A效价与对照组比较无差异(P>0.05)。结论:小鼠动物试验证实茵陈蒿汤可抑制ABO血型抗体的分泌。
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| 关 键 词： | 茵陈蒿汤 ABO血型 抗体 分泌 效价 抑制 |
Inhibitory effect of Yinchenhao decoction on secretion of ABO antibody from immune BALB/c mouse |
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| ZHOU Hua-You,YU Yan-Tao,ZHANG Wen,ZHANG Jian-Yuan,YANG He-Cai,LIU Chi-Xiang,WANG Shu-Hong,SHI Wen. Inhibitory effect of Yinchenhao decoction on secretion of ABO antibody from immune BALB/c mouse[J]. Chinese Journal of Immunology, 2011, 27(7): 607-610. DOI: 10.3969/j.issn.1000-484X.2011.07.007 |
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| Authors: | ZHOU Hua-You YU Yan-Tao ZHANG Wen ZHANG Jian-Yuan YANG He-Cai LIU Chi-Xiang WANG Shu-Hong SHI Wen |
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| Affiliation: | ZHOU Hua-You,YU Yan-Tao,ZHANG Wen,ZHANG Jian-Yuan,YANG He-Cai,LIU Chi-Xiang,WANG Shu-Hong,SHI Wen.Guangdong Provincial Hospital of Traditional Chinese Medicine,Guangzhou 510120,China |
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| Abstract: | Objective:To research the inhibitory effect of Yinchenhao decoction on secretion of ABO antibody from immune BALB/c.Methods:After BALB/c mice were immunized with erythrocyte of A blood group,the level of IgG anti-A of BALB/c mice in immune group and therapy group was investigated with indirect antiglobulin test(IAT),absorption and elution test,as well as titer detection of IgG anti-A antibody.Results:IgG anti-A of BALB/c mice in control group can not be detected while that can be detected in immune group;Ig... |
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| Keywords: | Yinchenhao decoction ABO blood group Antibody Secretion Titer Inhibition |
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