| 孕前体重指数和孕中期体重增加对妊娠期糖尿病发病影响的队列研究 |
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| 引用本文： | 毛雷婧,葛星,徐叶清,黄锟,潘维君,周珊珊,严双琴,陶芳标.孕前体重指数和孕中期体重增加对妊娠期糖尿病发病影响的队列研究[J].中华流行病学杂志,2015,36(5):416-420. |
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| 作者姓名： | 毛雷婧 葛星 徐叶清 黄锟 潘维君 周珊珊 严双琴 陶芳标 |
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| 作者单位： | 230032 合肥, 安徽医科大学公共卫生学院儿少卫生与妇幼保健学系 安徽人口健康与优生省级实验室;230032 合肥, 安徽医科大学公共卫生学院儿少卫生与妇幼保健学系 安徽人口健康与优生省级实验室;安徽省马鞍山市妇幼保健院;230032 合肥, 安徽医科大学公共卫生学院儿少卫生与妇幼保健学系 安徽人口健康与优生省级实验室;安徽省马鞍山市妇幼保健院;230032 合肥, 安徽医科大学公共卫生学院儿少卫生与妇幼保健学系 安徽人口健康与优生省级实验室;安徽省马鞍山市妇幼保健院;230032 合肥, 安徽医科大学公共卫生学院儿少卫生与妇幼保健学系 安徽人口健康与优生省级实验室 |
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| 基金项目： | 国家自然科学基金(81330068, 81373012) |
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| 摘 要： | 目的 探讨孕前BMI和孕中期体重增加对妊娠期糖尿病(GDM)患病的影响。方法 采用以孕妇人群作为基础的队列研究, 在安徽省马鞍山市妇幼保健院围生期门诊选取首次孕期体检、孕周≤14周、马鞍山市常住户口的孕妇, 首次、孕中期和孕晚期体检时分别填写问卷、测量身高和体重, 在24～28周接受75 g口服糖耐量试验(OGTT)进行GDM诊断, 并追踪记录分娩结局。使用t检验、方差分析、χ2检验和logistic回归模型进行分析。结果 孕妇GDM的发生率为14.73%, 孕前BMI与孕中期增重呈负相关(r=-0.085, P<0.01)。GDM孕妇孕中期增重多于正常孕妇。孕妇年龄≥35岁、孕前超重和肥胖及孕早期血糖水平升高是GDM的危险因素, OR值(95%CI)分别为3.06(1.68～5.58)、2.08(1.38～3.13)、3.73(1.84～7.56)和2.17(1.57～3.00)。结论 孕前超重和肥胖以及孕期体重增加是GDM的危险因素.
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| 关 键 词： | 糖尿病 妊娠期 体重指数 增重 队列研究 |
| 收稿时间： | 2014/10/28 0:00:00 |
Pregestational body mass index, weight gain during first half of pregnancy and gestational diabetes mellitus:a prospective cohort study |
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| Mao Leijing,Ge Xing,Xu Yeqing,Huang Kun,Pan Weijun,Zhou Shanshan,Yan Shuangqin and Tao Fangbiao.Pregestational body mass index, weight gain during first half of pregnancy and gestational diabetes mellitus:a prospective cohort study[J].Chinese Journal of Epidemiology,2015,36(5):416-420. |
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| Authors: | Mao Leijing Ge Xing Xu Yeqing Huang Kun Pan Weijun Zhou Shanshan Yan Shuangqin and Tao Fangbiao |
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| Affiliation: | Anhui Provincial Laboratory Population Health and Eugenics, Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei 230032, China;Anhui Provincial Laboratory Population Health and Eugenics, Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei 230032, China;Maternal and Child Health Care Center of Ma''anshan;Anhui Provincial Laboratory Population Health and Eugenics, Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei 230032, China;Maternal and Child Health Care Center of Ma''anshan;Anhui Provincial Laboratory Population Health and Eugenics, Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei 230032, China;Maternal and Child Health Care Center of Ma''anshan;Anhui Provincial Laboratory Population Health and Eugenics, Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei 230032, China |
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| Abstract: | |
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| Keywords: | Diabetes Gestation Body mass index Weight gain Cohort study |
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