血清过氧化氢酶活性测定的临床应用

应用比色测定法检测了１１５６例不同疾病患者的血清ＣＡＴ活性。与正常对照组比较，有３５８例不同疾病患者的血清ＣＡＴ活性增高，占疾病总数的３１．０％（Ｐ＜０．０１）。其中胰腺炎组为７６．５％（１３／１７）；胆囊炎组为４６．２％（６／１３）；肝癌组为５９．３％（１６／２７）；心衰组为５４．６％（６／１１）；非癌性肝病组为６４．６％（４２／６５）；精神分裂症组为５９．６％（５３／８９）。正常不同妊期妇血清ＣＡＴ活性在晚孕组校对照组明显增高，Ｐ＜０．０１。顺产与难产妇女血清ＣＡＴ活性和顺产与难产新生儿脐血清ＣＡＴ比较，结果均有差异（Ｐ＜０．０５）。

The Clinical Application of Determination of serum Cataiase Activity

We used the colorimetry determinationmethod for assesing the catalase(EC1,11,1,6;CAT)ac-tivity in serum of 1156 cases with different diseases.Com-paring with the normal group ,the serum CAT activity washighly increased in 358 cases with different diseases,which occupied 31.0%(P< 0.01 )of all cases.The ab-normal rate is 76.5%(13/17)in pancreatitis group; 46.2%(6/13)in cholecystitis group; 59.3%(16/27)in livertumor group;54.5%(6/11 )in heart failure group; 64.6%(42/ 65 )in noncancerous diseoses of liver;59.6%(53/ 89)in psychosis group.Comparing the serum CAT ac-tivity of the 85 cases of normal pregnant women in differ-ent pregnant period, the activity of later pregnant womenwas obviously higher than the controlled group(P<0.01).The serum CAT activity in dystacia women was higerthan in normal labor women(P<0.05).The umbilicalserum CAT activity in dystocia newborn was higher thanin normal newborn(P<0.05).