| EVOKED POTENTIALS OF OBSESSIVE-COMPULSIVE DISORDER： STATE OR TRAIT MARKER |
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| 引用本文： | 肖泽萍,陈兴时,张明岛,楼翡璎,陈珏. EVOKED POTENTIALS OF OBSESSIVE-COMPULSIVE DISORDER： STATE OR TRAIT MARKER[J]. 上海第二医科大学学报, 2004, 16(2): 79-82 |
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| 作者姓名： | 肖泽萍 陈兴时 张明岛 楼翡璎 陈珏 |
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| 作者单位： | Shanghai Institute of Mental Health，Teaching Aided Hospital of SSMU，Shanghai 200030，China，Shanghai Institute of Mental Health，Teaching Aided Hospital of SSMU，Shanghai 200030，China，Shanghai Institute of Mental Health，Teaching Aided Hospital of SSMU，Shanghai 200030，China，Shanghai Institute of Mental Health，Teaching Aided Hospital of SSMU，Shanghai 200030，China，Shanghai Institute of Mental Health，Teaching Aided Hospital of SSMU，Shanghai 200030，China |
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| 基金项目： | Supported by the Fund of ' 100 Distinguished Investigator' of Shanghai Sanitary Authorities(97BR030)，Fund of Clinical Medicine Center of Shanghai Mental Disorder(ZX02A14). |
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| 摘 要： | Objective To investigate the status of evoked potentials in obsessive-compulsive disorder(OCD). Methods Evoked potentials P300, auditory brainstem response (ABR) and visual evoked potential ( VEP) were recorded from 35 OCD patients and 28 normal controls (NC) with a Nicolet Spirit Instrument. 23 of the OCD patients were followed up after 5 months with the same markers. Results Compared with NC, OCD patients showed decreased P3 of P300 amplitude (OCD group 3. 5 ±1. 6μv vs. NC group 5.9 ±2. 1μv, P <0. 01), delayed V latency (6.4±0. 4ms vs. 5. 5 ±0. 3ms, P <0. 01) and increased V amplitude(0. 35±0. 1μv vs. 0. 16 ±0.09μv, P <0. 05) of ABR and delayed P2 of VEP latency (199±39ms vs. 183±28ms, P <0. 05). The follow-up measures of evoked potentials suggested that decreased P3 of P300 amplitude and delayed P2 of VEP latency might be state markers of OCD, while decreased V amplitude and delayed V of ABR latency might be trait markers of OCD. Conclusion The changes of P300 and VEP are related to clini
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| 关 键 词： | 强迫性失调 诱发电位 特征标记 OCD ABR 脑干 |
EVOKED POTENTIALS OF OBSESSIVE-COMPULSIVE DISORDER:STATE OR TRAIT MARKER |
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| XIAO Ze-ping CHEN Xing-shi ZHANG Ming-dao LOU Fei-yingCHEN Jue. EVOKED POTENTIALS OF OBSESSIVE-COMPULSIVE DISORDER:STATE OR TRAIT MARKER[J]. Journal of Shanghai Second Medical University(Foreign Language Edition), 2004, 16(2): 79-82 |
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| Authors: | XIAO Ze-ping CHEN Xing-shi ZHANG Ming-dao LOU Fei-yingCHEN Jue |
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| Affiliation: | XIAO Ze-ping CHEN Xing-shi ZHANG Ming-dao LOU Fei-yingCHEN JueShanghai Institute of Mental Health,Teaching Aided Hospital of SSMU,Shanghai 200030,China |
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| Abstract: | |
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| Keywords: | obsessive-compulsive disorder evoked potentials state marker trait marker |
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