Milk fat globule membrane – a source of polar lipids for colon health? A review |
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| Authors: | ANNA M KUCHTA PHILIP M KELLY CATHERINE STANTON ROSALEEN A DEVERY |
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| Affiliation: | 1. School of Biotechnology, Dublin City University, Dublin 9, Ireland;2. Food BioSciences Department, Moorepark Food Research Centre, Teagasc, Fermoy, Co. Cork, Ireland;3. Food Processing and Functionality Department, Moorepark Food Research Centre, Teagasc, Fermoy, Co. Cork, Ireland;4. National Institute for Cellular Biotechnology, Dublin City University, Dublin 9, Ireland |
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| Abstract: | The milk fat globule membrane (MFGM) surrounds fat globules, protects them against lipolysis and disperses the milk fat in the milk plasma. Besides their structural and emulsifying roles, in vivo and in vitro studies have demonstrated that phospholipids and sphingolipids of MFGM possess cancer risk‐reducing properties. Several reports attribute its chemopreventive activity to products of sphingomyelin hydrolysis, which affect multiple cellular targets that control cell growth, differentiation and apoptosis. With knowledge on the potential health benefits of MFGM lipids and proteins, dairy industries could in the future address their research in developing new functional dairy products enriched in beneficial MFGM components. |
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| Keywords: | Milk fat globule membrane Colon cancer Phospholipids Sphingolipids |
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