| 糖化血红蛋白作为糖尿病诊断指标的探讨 |
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| 引用本文： | 王梅华,张敬喜,罗心绮,曹颖平. 糖化血红蛋白作为糖尿病诊断指标的探讨[J]. 福建医科大学学报, 2011, 45(5): 371-373,380 |
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| 作者姓名： | 王梅华 张敬喜 罗心绮 曹颖平 |
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| 作者单位： | 福建医科大学附属协和医院检验科、医学技术与工程学院,检验系,福州,350001 |
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| 基金项目： | 福建省高校新世纪优秀人才计划资助项目(NCETFJ-0710) |
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| 摘 要： | 目的 探讨糖化血红蛋白(HbA1c)作为糖尿病(DM)诊断标准,对2型DM高危人群DM确诊的敏感度、特异度和准确度及其诊断DM切点的确定.方法 对334例2型DM高危人群,同一天检测其HbA1c和75 g-口服葡萄糖耐量试验(OGTT).按1999年WHO的DM诊断标准,得出其HbA1c累计频率分布表,绘制受试者工作特...
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| 关 键 词： | 血红蛋白A,糖基化 糖尿病 ROC曲线 |
Screening for Diabetes with Proposed Glycosylated Hemoglobin Based Diagnostic Criteria |
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| WANG Meihua,ZHANG Jingxi,LUO Xinyi,CAO Yingping. Screening for Diabetes with Proposed Glycosylated Hemoglobin Based Diagnostic Criteria[J]. Journal of Fujian Medical University, 2011, 45(5): 371-373,380 |
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| Authors: | WANG Meihua ZHANG Jingxi LUO Xinyi CAO Yingping |
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| Affiliation: | WANG Meihua,ZHANG Jingxi,LUO Xinyi,CAO YingpingDepartment of Clinical Laboratory,The Affiliated Union Hospital,Department of Laboratory Medicine,School of Medical Technology and Engineering,Fujian Medical University,Fuzhou 350001,China |
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| Abstract: | Objective To investigate the glycated hemoglobin(HbA1c) as a diagnostic criteria for diabetes mellitus(DM) and determine the cut-off point of HbA1c level and its sensitivity,specificity and accuracy in a population at high risk for type 2 diabetes.Methods OGTT was performed and HbA1c was measured in 334 subjects at high risk for type 2 diabetes on the same day.According to WHO diagnostic criteria of DM in 1999,the cumulative frequency distribution was acquired and the receiver operating characteristic(ROC) ... |
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| Keywords: | hemoglobin A glycosylated diabetes mellitus ROC curve |
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