| 首都医科大学长爪沙鼠群体遗传状况分析 |
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| 引用本文： | 孙贺娟,王冬平,王钜,李桂军,曹争和,孟霞,陈振文. 首都医科大学长爪沙鼠群体遗传状况分析[J]. 实验动物科学, 2006, 23(2): 1-5 |
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| 作者姓名： | 孙贺娟 王冬平 王钜 李桂军 曹争和 孟霞 陈振文 |
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| 作者单位： | 1. 军事医学科学院实验动物中心,北京,100071
2. 首都医科大学实验动物科学部,北京,100069 |
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| 基金项目： | 科技部科技基础条件平台建设计划;引进国际先进农业科技计划(948计划) |
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| 摘 要： | 为探讨首都医科大学长爪沙鼠群体的遗传状况,应用生化基因位点遗传检测方法,测定初始和生物净化长爪沙鼠群体27个生化位点等位基因的分布。结果表明,2个长爪沙鼠群体均具有丰富的遗传多样性;生物净化群体与初始群体比较有7.14%的基因丢失率,但尚未出现明显的遗传分化现象(FST<0.05);群体均偏离了哈迪-温伯格平衡(P<0.05)。
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| 关 键 词： | 长爪沙鼠 基因频率 遗传多样性 |
| 文章编号： | 1006-6179(2006)02-0001-05 |
| 收稿时间： | 2006-06-25 |
| 修稿时间： | 2005-11-01 |
Analysis of Population Genetic in Mongolian Gerbil of Capital University of Medical Sciences |
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| SUN He-juan,WANG Dong-ping,WANG Ju,LI Gui-jun,CAO Zheng-he,MENG Xia,CHEN Zhen-wen. Analysis of Population Genetic in Mongolian Gerbil of Capital University of Medical Sciences[J]. Laboratory Animal Science, 2006, 23(2): 1-5 |
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| Authors: | SUN He-juan WANG Dong-ping WANG Ju LI Gui-jun CAO Zheng-he MENG Xia CHEN Zhen-wen |
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| Abstract: | To study population genetic characteristic of Mongolian Gerbil of Capital University of Midical Sciences,27 loci of two colonies were determined by monitoring methods of biochemical markers.The result showed that the two colonies had high level of genetic diversity and low degree of genetic similarity;compared with the original colony,the biological purifying colony had 7.14% gene lost,but the two colonied did not appear obvious genetic differentiation(F-ST<0.05);the population deviated from Hardy-Weinberg equilibrium(P<0.05). |
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| Keywords: | Mongolian gerbil Gene frequencies Genetic diversity Genetic differentitation |
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