EMAb、血清β-HCG及黄体酮联合预测早孕先兆流产结局

目的 探讨抗子宫内膜抗体(EMAb)、人绒毛膜促性腺激素(β-HCG)、黄体酮联合检查预测早孕先兆流产结局的价值.方法 将早孕先兆流产120例病例根据保胎治疗后的妊娠结局分为两组,即保胎成功组78例、保胎失败组42例,分别检测治疗前后两组血清中EMAb,β-HCG及黄体酮的含量,以评价早孕先兆流产的预后.结果 检测两组患者血清中EMAb阳性率,保胎成功组为7.69%,保胎失败组为38.10%,保胎成功组中EMAb阳性率低(P<0.05);检测两组患者血清中β-HCG及黄体酮水平,在治疗前后保胎成功组均较保胎失败组高(P<0.05);两组患者经保胎治疗后血清β-HCG均较治疗前升高(P<0.05),而黄体酮无明显变化.结论 EMAb、β-HCG、黄体酮联合检查可更准确预测先兆流产结局,为临床诊疗提供理论依据.

EMAb,serum β-HCG and progesterone combined prediction of outcome of threatened abortion in early pregnancy

Objective To investigate the values pregnancy outcome of threatened abortion. Methods of EMAb, serum β-HCG, progesterone joint prediction of early 120 cases of threatened abortion pregnancy miscarriage treat- ment based on pregnancy outcomes were divided into two groups： miscarriage success group, miscarriage failure group. EMAb,β-HCG and progesterone in serum in two groups before and after treatment were measured to evaluate the prognosis of threatened abortion of early pregnancy. Results EMAb were detected in the serum of patients about positive rate, miscarriage success group was 7. 69%, miscarriage failure group was 38. 10%, miscarriage success group EMAb positive rate was significantly lower than miscarriage failure group （P〈0.05） ;β-HCG and progester- one in miscarriage success group were higher before and after treatment than miscarrgae failure group（P〈0.05） ;serum β-HCG were higher in two groups after treatment than before treatment（P〈0.05）,but progesterone had no sig- nificant difference before and after treatment. Conclusion EMAb, serum β-HCG, progesterone joint can accurately predict the outcome of threatened abortion,which provide the theoretical basis for clinical treatment.