CT引导下经皮穿刺活检术在骨骼病变诊断中的应用

目的探讨CT引导下骨骼病变穿刺活检技术的应用价值。方法2003年7月-2005年1月,48例患者接受CT引导下骨穿刺活检,其中34例有完整的临床资料,患者经扫描定位,选择最佳进针层面与路径,采用11～14 G骨穿针或18 G弹枪式活检针,局麻后将穿刺针刺入病灶,再次扫描确定穿刺针位置后,钻取标本,10%甲醛固定,送病理检查。结果整个操作过程耗时20～40 min,所有病例均取得了符合病理诊断要求的标本量,肯定病理诊断者30例,准确度91.2%,无操作相关并发症。结论CT引导骨穿刺活检是一种安全有效的骨骼病变的诊断手段,值得推广。

The experimental study of CT-guided hepatocyte growth factor gene therapy for cerebral ischemic diseases

Objective To evaluate the clinical value of CT-guided percutaneous biopsy for bone lesions.Methods Forty-Eight patients with different sited bone lesions had received the procedure of CT-guided percutaneous biopsy from July 2003 to January 2005,including 34 cases only with complete clinical records.The procedure was carried out with patient lied on CT table and followed by localization scanning to demonstrate the best sites for puncture and biopsy route.11-14 G bone puncture needle or 18 G trigger type biopsy needle was undertaken to penetrate into the lesion for obtaining specimens under local anesthesia and CT monitoring and in turn for fixation with 10% formalin to have pathologic examination.Results The whole procedure finished within 20-40 minutes with adequate samples obtained for pathologic examination of all cases.Confirmed diagnosis was made in 30 cases with an accuracy of 91.2% and no correlative complications were found.Conclusions The CT-guided percutaneous biopsy is safe and efficient for diagnosis of bone lesions,deserving to be extensively used.(J Intervent Radiol,2006,15: 603-606)