超高效液相色谱-串联质谱法测定 食品包装材料中双酚S含量

本文采用甲醇对食品包装材料进行超声提取,提取液经过滤后直接进行超高效液相色谱-串联三重四极杆质谱分析,从而测定食品包装材料中双酚S的含量。方法检出限为0.1 mg/kg。在0.5-20 mg/kg 范围内线性良好(相关系数为0.9993)。对空白样品进行双酚S的加标回收实验,平均回收率为89.6%-95.1%,相对标准偏差( n=6)为3.1%-7.9%,。该方法灵敏度高、抗干扰性强、重现性好,能够准确测定食品包装材料中双酚S的含量。

Determination of bisphenol S in food contact materials by ultra per-formance liquid chromatography-tandem mass spectrometry

This paper presents a method using methanol for the extraction of bisphenol S in food contact materials and high performance liquid chromatography for the direct determination of bisphenol S in extract after filtration. The LOD was 0.1 mg/kg. The correlation coefficients in the range of 0.5 - 20 mg/kg was 0.9993. The results spiked food contact materials showed that the average recoveries ranged from 89.6% to 95.1% while RSD% ranged from 3.1% to 7.9%. This method, of high sensitivity and reproducibility, is applicable for the precise determination of bisphenol S in food contact materials.