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浅析外泌体参与针刺调节作用的特点分析
引用本文:王美娟,李柠岑,陈波,陈勇,杨克俭,张靖宇,单凯,陈泽林,郭义. 浅析外泌体参与针刺调节作用的特点分析[J]. 天津中医药, 2022, 39(3): 325-329
作者姓名:王美娟  李柠岑  陈波  陈勇  杨克俭  张靖宇  单凯  陈泽林  郭义
作者单位:天津中医药大学实验针灸学研究中心, 天津 301617;天津中医药大学实验针灸学研究中心, 天津 301617;天津中医药大学针灸推拿学院, 天津 301617;国家中医针灸临床医学研究中心, 天津 300381;天津中医药大学实验针灸学研究中心, 天津 301617;国家中医针灸临床医学研究中心, 天津 300381;天津中医药大学中医学院, 天津 301617
基金项目:天津市教委科研计划项目(2017KJ143)。
摘    要:针灸作为一种物理刺激,在穴位局部被感知并转化传递到病变部位发挥效应的过程是复杂的.直至目前针灸的起效机制尚未完全阐明.外泌体作为细胞间通讯的新方式,前期研究发现针灸可以调控外泌体的释放,外泌体与针效之间关系密切,发现外泌体可能在针刺信息传递过程中发挥重要作用,是针刺信息传递的重要途径.外泌体具有分布广、来源广、运载物质...

关 键 词:外泌体特点  针灸作用特点  针灸机制  针灸转化
收稿时间:2021-02-01

A brief analysis of the characteristics of exosome participating in the regulation of acupuncture
WANG Meijuan,LI Ningcen,CHEN Bo,CHEN Yong,YANG Kejian,ZHANG Jingyu,SHAN Kai,CHEN Zelin,GUO Yi. A brief analysis of the characteristics of exosome participating in the regulation of acupuncture[J]. Tianjin Journal of Traditional Chin Medicine, 2022, 39(3): 325-329
Authors:WANG Meijuan  LI Ningcen  CHEN Bo  CHEN Yong  YANG Kejian  ZHANG Jingyu  SHAN Kai  CHEN Zelin  GUO Yi
Affiliation:Acupuncture Research Center, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China;Acupuncture Research Center, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China;College ofAcupuncture and Moxibustion, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China;National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China; Acupuncture Research Center, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China;National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China;College of Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Abstract:As a kind of physical stimulation,acupuncture is sensed locally at the acupoint and transferred to the lesion site to exert its effect is complex. Up to now,the effective mechanism of acupuncture has not been fully clarified. As a new way of intercellular communication,our previous studies found that acupuncture can regulate the release of exocrine,and there is a close relationship between exocrine and acupuncture effect. It is found that exocrine may play an important role in the process of acupuncture information transmission. It is an important way of acupuncture information transmission. The exosome body has the characteristics of wide distribution,wide source,many carrying substances,many effects,targeted transportation,tissue source specificity,clinical application safety and stability,and so on. It may be closely related to the whole network regulation of acupuncture and moxibustion,"qi to disease place",viscera-meridian acupoint correlation,acupuncture serum drug conversion application and so on. This paper combs and analyzes the characteristics of exocrine and acupuncture in order to explain the principle of acupuncture and moxibustion. To provide new ideas for promoting clinical transformation of basic research on acupuncture and moxibustion.
Keywords:exosome characteristics  the characteristics of acupuncture and moxibustion  mechanism of acupuncture  transformation of acupuncture
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