| 大鼠Ⅲ度烫伤后异体、自体皮混合移植局部透明质酸含量的变化 |
| |
| 引用本文： | 丁韧,赵雁飞,王莉. 大鼠Ⅲ度烫伤后异体、自体皮混合移植局部透明质酸含量的变化[J]. 中华烧伤杂志, 2000, 16(1): 43-45 |
| |
| 作者姓名： | 丁韧 赵雁飞 王莉 |
| |
| 作者单位： | [1]上海第二医科大学瑞金医院烧伤研究所，200025 [2]上海第二医科大学病理学教研室 |
| |
| 基金项目： | 国家自然科学基金资助(39290700) |
| |
| 摘 要： | 目的 探讨混合移植皮片中细胞外间质的变化。方法 采用放射免疫方法测定了大鼠Ⅲ度烫伤后混合移植(异体皮打洞嵌植自体皮片)后3、5、7、14、21、28d自体皮区和异体皮区透明质酸的含量变化。结果 移植后自体皮区和异体皮区透明质酸含量变化均是先下降后上升，但自体皮区升高早于异体皮区，在移植后第14天(嵌植第12天)即开始显升高，至28d仍显高于正常对照，而异体皮区在移植后第21天才显升高，升高幅度也无自体皮区明显。结论 在植皮同时适当外用透明质酸可能更有利于移植皮区的愈合和重建。
|
| 关 键 词： | 大鼠 Ⅲ度烫伤 异体皮移植 自体皮移植 混合移植 透明质酸 |
| 修稿时间： | 1999-04-15 |
The change in hyaluronic acid ( HA ) in auto-and allo-skin intermingled grfting in extensive full thickness burn in rat model |
| |
| DING Ren,ZHAO Yanfei,WANG Li. The change in hyaluronic acid ( HA ) in auto-and allo-skin intermingled grfting in extensive full thickness burn in rat model[J]. Chinese journal of burns, 2000, 16(1): 43-45 |
| |
| Authors: | DING Ren ZHAO Yanfei WANG Li |
| |
| Affiliation: | DING Ren,ZHAO Yanfei,WANG Li(Shanghai Burn Institute, Rui Jin Hospital, Shanghai Second) |
| |
| Abstract: | Objective To elucidate the changes in hyaluronic acid (HA) contents in auto-and alloskin intermingled grafting. Method HA was determined by rado-immunoassay in auto-and alloskin intermingled grafting (a large sheet of allograft inlaid with small stamps of autoskin) in experimental extensive full-thickness burn rats on 3rd,5th,7th, 14th,21st, 28th postoperation days. Results In both areas of intermingled skin grafting,the contents of HA was reduced first and in- creased significantly thereafter, but the contents in auto-skin areas rose earlier and higher than those in allo-ones. Conclusion The results suggest that adequate application of HA may be beneficial to the healing and remodelling of grafted area. |
| |
| Keywords: | Hyaluranic acid Intermingled grafting Burn Wound healing |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
