| 肺心病患者尿检视黄醇结合蛋白及转铁蛋白的临床意义 |
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| 引用本文： | 李洪,王晓东,冯玉锡,李元桂,辛建保,杨国昌.肺心病患者尿检视黄醇结合蛋白及转铁蛋白的临床意义[J].华中科技大学学报(医学版),1999,28(5):405-406. |
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| 作者姓名： | 李洪 王晓东 冯玉锡 李元桂 辛建保 杨国昌 |
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| 作者单位： | 同济医科大学附属协和医院内科,武汉,430022 |
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| 摘 要： | 采用酶联免疫法检测２４ 例肺心病患者和３０ 例健康中老年人的尿视黄醇结合蛋白 （ＲＢＰ）， 转铁蛋白（ＴＲＦ） 水平。同时测定其血尿素氮（ＢＵＮ）， 肌酐 （Ｃｒ）。结果： 肺心病患者尿ＲＢＰ、ＴＲＦ水平较对照组显著升高 （Ｐ＜ ０．０１），其中合并心衰患者较无合并心衰者的尿ＲＢＰ、ＴＲＦ水平有显著性差异（Ｐ＜ ０．０１）。表明患肺心病患者确存在肾功能的损害， 动态观察尿ＲＢＰ、ＴＲＦ水平变化是判断其早期肾功能损害的敏感方法， 能够早期发现肺心病患者的肾功能损害并判断其损害部位及程度
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| 关 键 词： | 肺心病 尿视黄醇结合蛋白 尿转铁蛋白 肾功能 |
| 修稿时间： | :1999-01-1 |
Clinical Implication of Retinal-binding-protein and Transferrin in Urine in Patients with Cor Pulmonale |
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| LiHong,Wang Xiaodong,Feng Yuxietal Departm entof InternalMedicine,Xiehe Hospital,TongjiMedicalUniversity,Wuhan.Clinical Implication of Retinal-binding-protein and Transferrin in Urine in Patients with Cor Pulmonale[J].Journal of Huazhong University of Science and Technology(Health Sciences),1999,28(5):405-406. |
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| Authors: | LiHong Wang Xiaodong Feng Yuxietal Departm entof InternalMedicine Xiehe Hospital TongjiMedicalUniversity Wuhan |
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| Affiliation: | LiHong,Wang Xiaodong,Feng Yuxietal Departm entof InternalMedicine,Xiehe Hospital,TongjiMedicalUniversity,Wuhan 430022 |
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| Abstract: | The levelof retinal-binding-protein (RBP) and transferrin (TRF) w as m easured by using ELISA in urine of 24 patients w ith cor pulm onale and 30 health subjects. It w as found that the levels of RBP and TRFin the patients w ith cor pulm onale w ere significantly higher than in health subjects (P< 0.01) . RBP and TRF levels in the cor pulm onale patients associated w ith right heart breakdow n w ere greatly differentfrom those w ithoutheartbreakdow n (P< 0.01). The results show ed thatthe dam ages to kidney function in the patients w ith corpulm onale existed indeed. The dynam ic observation ofthe levels of RBPand TRFw as a sentive m ethod for estim ating early renalfunction dam age. |
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| Keywords: | cor pulm onale retinal-binding-protein transferrin kidney function |
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