| 活血化瘀药干预糖尿病心血管风险因素的系统评价 |
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| 引用本文： | 黄苏萍,邱彩霞,林妙娴,陈龙辉,衡先培,张松峰,纪春敏.活血化瘀药干预糖尿病心血管风险因素的系统评价[J].中华中医药杂志,2011(6):1410-1415. |
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| 作者姓名： | 黄苏萍 邱彩霞 林妙娴 陈龙辉 衡先培 张松峰 纪春敏 |
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| 作者单位： | 福建中医药大学;福建省人民医院; |
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| 基金项目： | 福建省卫生厅中医药科研项目(No.WZY0920)~~ |
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| 摘 要： | 目的:评价活血化瘀药干预糖尿病心血管风险因素的临床疗效和安全性。方法:运用循证医学Cochrance系统评价方法,检索PubMed、CNKI、VIP、CBM、中国博硕士学位论文全文数据库等,检索时间截止为2010年12月,纳入国内外有关活血化瘀药干预糖尿病心血管风险因素的随机对照试验(RCT)。应用Jadad评分评价纳入文献质量,选择空腹血糖(FBG)、餐后2h血糖(P2BG)、糖化血红蛋白(HbA1c)、甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白(HDL-c)、低密度脂蛋白(LDL-c)、心电图(ECG)、心绞痛疗效与中医证候疗效等10项结局指标,运用RevMan 5.0软件进行Meta分析。结果:共纳入16个RCT,共计1 634例患者。Jadad评分:5分的8篇,3分的5篇,2分的3篇。Meta分析显示,HbA1C、HDL-c、ECG、中医症候疗效及心绞痛疗效等5项指标与对照组比较有统计学差异(P<0.05),其他指标没有统计学差异。西药联合活血化瘀中药治疗在一定程度上优于单独的西药或安慰剂治疗,且未见不良反应,安全可靠。结论:现有证据表明,活血化瘀中药干预糖尿病心血管风险因素有一定的效果。受纳入研究数量与质量的限制,其疗效和安全性期待更多高质量的随机双盲对照试验加以证实。
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| 关 键 词： | 糖尿病 心血管 风险因素 活血化瘀 系统评价 Meta分析 随机对照试验 |
Systematic review on drug for invigorating blood circulation and eliminating stasis intervening in the risk factors of diabetes combining with cardiac-blood vessel disease |
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| HUANG Su-ping,QIU Cai-xia,LIN Miao-xian,CHEN Long-hui,HENG Xian-pei,ZHANG Song-feng,JI Chun-min.Systematic review on drug for invigorating blood circulation and eliminating stasis intervening in the risk factors of diabetes combining with cardiac-blood vessel disease[J].China Journal of Traditional Chinese Medicine and Pharmacy,2011(6):1410-1415. |
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| Authors: | HUANG Su-ping QIU Cai-xia LIN Miao-xian CHEN Long-hui HENG Xian-pei ZHANG Song-feng JI Chun-min |
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| Affiliation: | HUANG Su-ping1, QIU Cai-xia1, LIN Miao-xian1, CHEN Long-hui1, HENG Xian-pei2, ZHANG Song-feng1, JI Chun-min1(1Fujian University of TCM, Fuzhou 350108, China; 2The People’s Hospital of Fujian Province, Fuzhou 350004, China) |
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| Abstract: | Objective: To assessment the curative effect and the security of drug for invigorating blood circulation and eliminating stasis intervening in the risk factors of diabetes combining with cardiac-blood vessel disease. Methods: Through retrieval Cochrane, MEDLINE, CNKI, VIP, CBM, Full-text data base of Chinese Drs and Lics, search time cut off in 2010.12. RCTs related drug for invigorating blood circulation and eliminating stasis intervening in the risk factors of diabetes combining with cardiac-blood vessel ... |
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| Keywords: | Diabetes Cardiac-blood vessel disease Risk factors Invigorating blood circulation and eliminating stasis Systematic review Meta analysis RCT |
| 本文献已被 CNKI 等数据库收录！ |
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