工作场所空气中正丙醇测定方法研究

目的 研究并建立适用于工作场所空气中正丙醇的定量检测方法。
方法 工作场所空气中正丙醇由活性炭管采集, 经体积比为1:100的异丙醇-二硫化碳混合溶剂解吸后, 经石英弹性毛细管柱HP-INNOWAX (30.0 m×0.53 mm×1.0μm)分离, 氢焰离子化检测器检测, 标准曲线法定量。
结果 正丙醇浓度在10~500 μg/mL范围内和峰面积呈线性关系, 回归方程y=2.12 x+1.96, 相关系数r=0.999 9(P < 0.05)。以3.0 L采样量计, 方法最低检出浓度0.09 mg/m3, 最低定量浓度0.30 mg/m3; 不同浓度加标样品测定结果的相对标准偏差为1.7%~3.6%, 解吸效率89.3%~94.7%, 采样效率> 96%, 100 mg活性炭对正丙醇的穿透容量为16 mg; 采样后的活性炭管在室温条件下至少可放置7 d。
结论 建立的工作场所空气中正丙醇溶剂解吸-气相色谱测定方法准确可靠、灵敏度高、稳定性良好, 适用于工作场所空气中正丙醇的现场检测。

Study on method for determination of n-Propanol in the air of workplaces

Objective To establish a method for the quantitative determination of n-propanol in the air of workplaces. Methods The charcoal tubes were used for collection of airborne n-propanol in workplaces, and the 1% isopropanol-carbon disulfide mixture solvent was used for desorption. The analytes were separated with capillary column HP-INNOWAX (30.0 m×0.53 mm×1.0 μm), then detected with FID and quantified with standard curve method. Results The liner range of n-propanol concentrations was 10 to 500 mg/L with the regression equation y=2.12 x + 1.96, and the correlation coefficient(r) was 0.999 9(P < 0.05). The limit of quantitation (LOQ) of n-propanol in air was 0.30 mg/m3 and the concentration of analytes in air was 0.09 mg/m3 based on the sampling volume (3.0 L). The relative standard deviations (RSD) varied from 1.7% to 3.6%. The desorption efficiencies varied from 89.3% to 94.7% and the sampling efficiency was more than 96%. The breakthrough volume was 16 mg of n-propanol in 100 mg of active carbon. The activated carbon tubes after sampling can be stored at room temperature for 7 days. Conclusion This method applied solvent desorption with gas chromatographic method for determination of n-propanol in the air of workplaces was of high sensitivity, and good stability, which is appropriate for the field monitoring of n-propanol in the air of workplaces.