| 人参总皂甙对小鼠骨髓基质细胞RNA表达及其细胞因子诱生的影响 |
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| 引用本文： | 杨世成,王树和.人参总皂甙对小鼠骨髓基质细胞RNA表达及其细胞因子诱生的影响[J].中国药理学通报,1994,10(1):40-43. |
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| 作者姓名： | 杨世成 王树和 |
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| 作者单位： | 白求恩医科大学基础免疫教研室 |
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| 摘 要： | 采用胶片法（细胞贴壁胶片生长法）及放射自显影等技术，较系统地观察了人参总甙（ＴＧＳ）对小鼠骨髓基质细胞ＲＮＡ表达的时相特点及对细胞因子ＩＬ－３、１１－６诱生的影响。结果表明．ＴＧＳ在体外对小鼠骨髓基质细胞ＲＮＡ的代谢有明显的促进效应．并且发现骨髓基质细胞实验上清中ＩＬ－３、ＩＬ－６因子的活性显著高于正常对照组。在此基础上。又利用放射自显影技术做为胶片法可行性的佐证．取得满意结果。
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| 关 键 词： | 人参总皂甙，骨髓基质细胞，小鼠胶片法，放射自显影 |
^ Effects of panax ginshenoside on RNA expression and cytokine induction of BMSC by jiaopian technique |
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| YANG Shi-Cheng, WANG Shu-He, ZHANG Dong-Ji, et al.^ Effects of panax ginshenoside on RNA expression and cytokine induction of BMSC by jiaopian technique[J].Chinese Pharmacological Bulletin,1994,10(1):40-43. |
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| Authors: | YANG Shi-Cheng WANG Shu-He ZHANG Dong-Ji et al |
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| Abstract: | Effects of panax ginshenoside (PGS) on RNA expression and IL-6、 IL-3 induction of bone marrow stromal cell(BMSC) were observed systematically by applying Jiaopian technique(a new method for studying stromal cells)and radioautography etc.The results showed that PGS could stimulate synthesis of RNA metabolism of BMSC in vitro,and it could enhance the activity of IL-6 IL-3 in experimental supernants of BMSC compared with normal control.With the aids of radioautography,Jiaopian technique was found to be very convenient for studying RNA DNA metablism of stromal cells. |
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| Keywords: | panax ginshenoside bonemarrow stromal cell mice jiaopian assay radioautography |
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