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国产瑞替普酶联合磺达肝癸钠治疗急性ST段抬高性心肌梗死32例临床分析
引用本文:李成洋,王肖,苗志林,程丽,杜洪洋,汪丽,姜仲卓,于倩,李占全.国产瑞替普酶联合磺达肝癸钠治疗急性ST段抬高性心肌梗死32例临床分析[J].临床心血管病杂志,2012(9):678-679.
作者姓名:李成洋  王肖  苗志林  程丽  杜洪洋  汪丽  姜仲卓  于倩  李占全
作者单位:辽宁省人民医院心血管内科
摘    要:目的:总结国产瑞替普酶联合磺达肝癸钠治疗急性ST段抬高性心肌梗死(STEMI)的临床疗效和安全性。方法:收集2011-03-2011-10我院年龄≤75岁的STEMI患者32例,给予国产瑞替普酶联合磺达肝癸钠治疗,观察临床效果。结果:90min临床判断血管再通24例(75.0%),5例(15.6%)患者接受介入治疗,全部患者住院期间无严重出血、过敏及死亡事件发生。结论:国产瑞替普酶联合磺达肝癸钠是STEMI患者再灌注治疗用药的理想组合。

关 键 词:心肌梗死  国产瑞替普酶  磺达肝癸钠

Efficacy and safety of homemade reteplase and fondaparinux as reperfusion therapy in 32 patients with acute ST-segment elevation myocardial infarction
LI Chengyang,WANG Xiao,MIAO Zhilin,CHENG Li,DU Hongyang,WANG Li,JIANG Zhongzhuo,YU Qian,LI Zhanquan.Efficacy and safety of homemade reteplase and fondaparinux as reperfusion therapy in 32 patients with acute ST-segment elevation myocardial infarction[J].Journal of Clinical Cardiology,2012(9):678-679.
Authors:LI Chengyang  WANG Xiao  MIAO Zhilin  CHENG Li  DU Hongyang  WANG Li  JIANG Zhongzhuo  YU Qian  LI Zhanquan
Affiliation:(Department of Cardiology,Liaoning Provincial People’s Hospital,Shenyang,110016,China)
Abstract:Objective:To study the efficacy and safety of homemade reteplase and fondaparinux used for thrombolysis therapy in patients with acute ST segment elevation myocardial infarction(STEMI). Method:From Mar 2011 to Oct 2011,a total of 32 STEMI patients(≤75 years old) was cured by homemade reteplase and fondaparinux,and the clinical effects were observed. Result:Twenty-four patients had clinical vascular recanalization(90 minutes),5 patients received PCI.There was no severe hemorrhage,allergy and death in all patients. Conclusion:It is safe and efficient to use homemade reteplase and fondaparinux for reperfusion therapy in patients with STEMI.
Keywords:myocardial infarction  homemade reteplase  fondaparinux
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