神经纤维瘤病的临床、影像学表现分析(附11例报告)

目的 探讨神经纤维瘤病的临床和影像学特征,复习文献,提高诊断率.方法 回顾性分析我院2003-2009年经临床和病理证实的神经纤维瘤病11例.结果 NF1型7例,3例累及脊柱、肋骨,2例为皮下神经纤维瘤,2例为颈部、胸廓入口及腹腔神经纤维瘤并视神经胶质瘤.累及骨骼者主要表现为:(1)脊柱后缘弧形压迹,椎间孔增大.(2)...

Analysis of clinical and imaging finding with neurofibromatosis(Report of 11 cases)

Objective To investigate the imaging and clinical features of neurofibromatosis,at the same time,the latest correlated paper were also reviewed.Methods The study included 11 patients with neurofibromatosis,which were proven by the clinic features and the pathology,in our hospital between 2003 and 2009.Result Neurofibromatosis was found in NFI(n=7) and NFII(n=4).There were 3 cases of NFI,involving the spine and the ribs,and the manifestations were as follows:①The posterior margin of arc pressure trace,increasing intervertebral foramen.②Scoliosis deformity,joint dislocation separation.③Rib hypoplasia,neck thinner,and see arc voltage trace.④Spondylolisthesis,local bone is unclear,spondylolysis have defects,smaller malformations.2 cases of NF1 had multiple neurofibromatosis in the soft tissues,and the other 2 cases had multiple neurofibromatosis in the neck,mediastinum and abdominal cavity,combining with gioma of optic nerve.The main findings of 4 cases of NFII,included unilateral or bilateral acoustic,multiple meningiomas neuroma,Optic nerve glioma,Inside and outside the spinal canal tumor,etc.Café au lait spots were found in NFI(n=4) and NFII(n=1).Only 2 cases with neurofibromatosis have a hereditary form of this disease.Conclusion Neurofibromatos can be definitely diagnosed,basing on comprehensive analysis of imaging features and typical syndromes.