Th1 cell development induced by cysteine proteinases A and B in localized cutaneous leishmaniasis due to Leishmania guyanensis |
| |
| Authors: | Pascalis Hervé Lavergne Anne Bourreau Eliane Prévot-Linguet Ghislaine Kariminia Amina Pradinaud Roger Rafati Sima Launois Pascal |
| |
| Affiliation: | Immunologie des Leishmanioses, Institut Pasteur de le Guyane Fran?aise, Institut d'Etudes Supérieures de la Guyane, Université Antilles-Guyane, Cayenne, French Guiana. |
| |
| Abstract: | The cysteine proteinases CPA and CPB from Leishmania major induced Th1 responses in patients with leishmaniasis due to Leishmania guyanensis. Furthermore, cysteine proteinases induced neither interleukin 4 (IL-4) nor IL-13 and low levels of IL-10 in controls and patients. The results suggest that CPs would be quite good candidates for a vaccine against different Leishmania species. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
