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阿托伐他汀对脑缺血再灌注损伤保护作用的研究进展
引用本文:万玉红,王旋,张红菱. 阿托伐他汀对脑缺血再灌注损伤保护作用的研究进展[J]. 武汉食品工业学院学报, 2013, 0(4): 93-97
作者姓名:万玉红  王旋  张红菱
作者单位:[1]武汉轻工大学校医院,湖北武汉430023 [2]武汉轻工大学医学技术与护理学院,湖北武汉430023
摘    要:脑缺血再灌注损伤在形成和发展的过程中会引起一系列炎症因子的变化,阿托伐他汀能够通过对炎症因子直接或者间接的抑制来实现对脑缺血再灌注损伤的保护。本文对脑缺血再灌注损伤时炎症因子的免疫学机制及阿托伐他汀的保护作用进行综述,为脑缺血再灌注损伤保护作用的进一步研究提供理论依据。

关 键 词:缺血再灌注损伤  阿托伐他汀  炎症因子  保护作用

Research progress on the protection effect of Atorvastatin against cerebral ischemia reperfusion injury
WAN Yu-hong,WANG Xuan,ZHANG Hong-ling. Research progress on the protection effect of Atorvastatin against cerebral ischemia reperfusion injury[J]. , 2013, 0(4): 93-97
Authors:WAN Yu-hong  WANG Xuan  ZHANG Hong-ling
Affiliation:1. The Hospital of Wuhan Polytechnic University, Wuhan Polytechnic University ,Wuhan 430023, China; 2. School of Health Science and Nursing, Wuhan Polytechnic University, Wuhan 430023, China)
Abstract:The cerebral ischemia reperfusion injury can cause a series of inflammatory factor's change in the process of formation and development,and atorvastatin can protect cerebral ischemia reperfusion injury by inhibiting inflam- mation factor directly or indirectly. This paper reviews the immunology mechanism of inflammation factor on cere- bral ischemia reperfusion injury and atorvastatin's protection,and provides theoretical basis for further study.
Keywords:ischemia reperfusion injury  atorvastatin  inflammation factor  protection effect
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