利用肿瘤医院资源优势开展临床流行病学研究

肿瘤医院具有独特的资源优势。利用临床流行病学方法，收集、利用肿瘤病例信息、肿瘤临床诊治、肿瘤生物标本等信息资源，可以促进新形势下肿瘤医院管理和科研的深入发展。南通市肿瘤医院是三甲肿瘤专科医院，也是国内最早开展肿瘤诊治的地市级肿瘤专科医院之一，已具备了开展临床流行病学研究、医学随访研究及完善样本库并应用的工作基础。本文内容包括建立以医院为基础的肿瘤登记系统、为开展临床流行病学服务；建立临床肿瘤病例的随访与调查制度，评估肿瘤治疗影响因素并开展生存率分析；建立具有完善流行病学信息背景的肿瘤病例生物标本库，以适应转化医学发展之需。对工作中存在的瓶颈问题也进行了讨论。

To take advantage of tumor hospital resources for clinical epidemiological study

The tumor hospital has its unique resources superiority. To collect and utilize the in- formation from tumor patients, information from thcir diagnosis and treatment, and biological speci- mens, through clinical epidemiology methods and design, would facilitate the deep development in the management and research at tumor hospitals in the new circumstances. Nantong Tumor Hospital, a first-rate 3A hospital, and also one of the earliest-run specialized tumor hospitals in prefecture-level cities, possesses own basis for clinical epidemiologi~al research, medical follow-up, and application of biobanking. In this paper we report the specific work plan and work contents, including： to establish a hospital-bascd cancer registry system for serving clinical epidemiology; to set up a follow-up system for clinical cases with tumor, in order to assess the effect of factors on tumor treatment and to analyse their survival rates; to build a biobank of tumor cases with perfect epidemiological information and background, fitting in with the needs of the development of translational medicine. The bottleneck problems in the work are also discussed.