高压氧综合治疗急性脑梗死一年期内疗效分析

目的 探讨脑梗死急性期行高压氧治疗对患者1年内神经功能恢复的影响.方法 急性脑梗死患者192例分为高压氧组和非高压氧组,分别于治疗前、治疗20 d、3个月、6个月、12个月时进行神经功能缺损评分对比.根据治疗前神经功能缺损评分,每组患者冉被分为轻、中、重3个亚组进行分析.结果 (1)神经功能缺损轻型组:治疗后各评分时间高压氧组均较非高压氧组有显著改善(P<0.01或P<0.05).(2)神经功能缺损中型组:高压氧20 d组、12个月组较同期非高压氧组有明显改善,差异有统计学意义(P<0.05).(3)神经功能缺损重型组:高压氧6个月组、12个月组较同期非高压氧组有明显改善,差异有统计学意义(P<0.05).(4)高压氧组1年死亡率较非高压氧组有明显降低,差异有统计学意义(P<0.01).高压氧组1年复发率较非高压氧组有明显降低,差异有统计学意义(P<0.05).结论 脑梗死患者急性期行高压氧治疗不仪可以改善患者急性期神经缺损,而且在1年内仍可使患者受益,改善神经功能,降低死亡率及复发率.

Curative effects of hyperbaric oxygen combined therapy for the patients with one-year acute cerebral infarction

Objective To explore curative effects of hyperbaric oxygen ( HBO) combined therapy for the patients with one-year acute cerebral infarction. Methods One hundred and ninty-two patients with acute cerebral infarction were divided randomly into HBO group and control group. The neurological impairment was scored before and after 20 days, 3 months, 6 months and 12 months of HBO therapy,respectively. According to the severity of neurological impairment before therapy, each group was divided into three subgroups. Results (1) Slight neurological impairment group: neurological impairment scores of HBO group were significantly lower than those of simultaneous control group( P <0. 01 or P <0.05 ). (2) Moderate neurological impairment group: neurological impairment scores of HBO group after 20 days and 12 months were significantly lower than those of simultaneous control group ( P < 0. 05 ). (3) Sever neurological impairment group: neurological impairment scores of the HBO group after 6 and 12 months were significantly lower than those of simultaneous control group (P <0. 05). (4) Both one-year mortality and relapse rate were significantly lower in the HBO group than those in control group (P <0. 01or P <0. 05). Conclusions During the acute stage, HBO therapy can improve neurological function recovery and benifit the patients after one-year acute of cerebral infarction. At the same time, HBO therapy can cut down the rate of mortality and relapse.