| 组织工程化软骨修复关节软骨缺损 |
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| 引用本文： | 许荣耀,张寿.组织工程化软骨修复关节软骨缺损[J].中国组织工程研究与临床康复,2011,15(41). |
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| 作者姓名： | 许荣耀 张寿 |
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| 作者单位： | 中南大学湘雅医学院附属海口医院骨科中心,海南省海口市,570208 |
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| 摘 要： | 背景:目前治疗软骨缺损的方法均有明显缺陷,组织工程软骨修复关节软骨缺损为微创治疗软骨缺损提供了新方法.目的:总结组织工程软骨应用于修复关节软骨缺损的新进展.方法:由第一作者用计算机检索万方数据库(2000/2010)和PubMed 数据库(2000/2010),检索词分别为"软骨缺损,组织工程软骨"和"articular cartilage defects,tissue-engineered cartilage ",语言分别设定为中文和英文.从组织工程软骨及其新进展2 方面进行总结,对组织工程软骨的发展及构建等方面进行介绍.共检索到666 篇文献,按纳入和排除标准对文献进行筛选,共纳入23 篇文章.结果与结论:近年来随着细胞支架材料的不断发展和组织构建技术的日趋成熟,结合活性细胞和支架的组织工程软骨为微创修复关节软骨缺损提供了良好的治疗手段及方法,组织工程软骨修复软骨缺损是完全可行的,C-GP 凝胶与种子细胞相容性好,可做为组织工程软骨的理想支架,但细胞支架的制备及选择仍然是组织工程软骨的热点和难点.
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| 关 键 词： | 组织工程软骨 关节软骨 缺损 支架 软组织构建 |
Tissue-engineered cartilage for treatment of articular cartilage defects |
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| Xu Rong-yao,Zhang Shou.Tissue-engineered cartilage for treatment of articular cartilage defects[J].Journal of Clinical Rehabilitative Tissue Engineering Research,2011,15(41). |
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| Authors: | Xu Rong-yao Zhang Shou |
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| Affiliation: | Xu Rong-yao,Zhang Shou Department of Orthopedics,Haikou Hospital Affiliated to Xiangya School of Medicine,Central South University,Haikou 570208,Hainan Province,China |
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| Abstract: | BACKGROUND:At present,the methods for treatment of articular cartilage defects have obvious shortcomings.Tissue-engineered cartilage for repair of articular cartilage defects provides a novel method to treat cartilage defects with minimal invasion.OBJECTIVE:To summarize the research progress in tissue-engineered cartilage for repair of articular cartilage degects.METHODS:A computer-based retrieval was performed by the first author in the Wanfang data(2000/2010)and Pubmed database(2000/2010) using the key wo... |
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| 本文献已被 CNKI 万方数据 等数据库收录！ |
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