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| 血清HCV RNA检测在预防输血后丙型肝炎中的意义 | |
| 引用本文： | 张英,李晶,刘玉风,赵宏伟,田庚善.血清HCV RNA检测在预防输血后丙型肝炎中的意义[J].中华实验和临床病毒学杂志,2006,20(1):70-72. |
| 作者姓名： | 张英 李晶 刘玉风 赵宏伟 田庚善 |
| 作者单位： | 1. 150036,哈尔滨,黑龙江省医院感染内科 2. 150036,哈尔滨,黑龙江省医院检验科 3. 北京大学第一医院感染疾病科 |
| 摘 要： | 目的 探讨血清HCV RNA检测在预防输血后丙型肝炎中的意义。方法 用ELISA法检测2000年1月至2003年12月末抗．HCV阴性的全血标本56400份次，再进行RT-PCR（荧光适时技术）检测HCV RNA，并对输过HCV RNA筛查阴性血液的患者进行追查。结果 HCVRNA阳性率为2．5‰（146／56400）。对输过HCVRNA筛查阴性血液的患者追查结果，无一例发生输血后丙型肝炎。结论 对抗-HCV阴性的血液标本用敏感的试剂进行HCV RNA检测在预防输血后丙型肝炎中不但有效，而且可行。 |
| 关 键 词： | 肝炎病毒 RNA 输血传播病毒 肝炎 丙型 |
| 修稿时间： | 2005年8月15日 |
Significance of blood HCV RNA screening in the prevension of post-transfusion hepatitis C |
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| ZHANG Ying,LI Jing,LIU Yu-feng,ZHAO Hong-wei,TIAN Geng-shan.Significance of blood HCV RNA screening in the prevension of post-transfusion hepatitis C[J].Chinese Journal of Experimental and Clinical Virology,2006,20(1):70-72. | |
| Authors: | ZHANG Ying LI Jing LIU Yu-feng ZHAO Hong-wei TIAN Geng-shan |
| Affiliation: | Department of Infectious Diseases, Heilongjiang Provincial Hospital, Harbin 150036, China. |
| Abstract: | BACKGROUND: To investigate the significance of blood HCV RNA screening in the prevention of post-transfusion hepatitis C. METHODS: Totally 56,400 anti-HCV negative blood samples collected from Jan. 2000 to Dec. 2003 were tested for HCV RNA by RT-PCR, and the patients who received the HCV RNA negative blood were followed up. RESULTS: The HCV RNA positive rate was 2.5 per thousand (146/56,000) and none of the patients followed up suffered from HCV infection. CONCLUSION: HCV RNA screening for the anti-HCV negative blood samples is very effective and feasible for prevention of post-transfusion hepatitis C. |
| Keywords: | Hepacivirus RNA Trasfusion-transmitted virus Hepatitis C |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |
