| P-QuantWiz:一种基于质谱的并行非标记定量软件 |
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| 引用本文： | 胡泽林,张云泉,王靖,张先轶.P-QuantWiz:一种基于质谱的并行非标记定量软件[J].计算机工程与科学,2009,31(11). |
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| 作者姓名： | 胡泽林 张云泉 王靖 张先轶 |
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| 作者单位： | 1. 中国科学院软件研究所并行计算实验室,北京,100190;中国科学院计算机科学国家重点实验室,北京,100190;中国科学院研究生院,北京,100049
2. 中国科学院软件研究所并行计算实验室,北京,100190;中国科学院计算机科学国家重点实验室,北京,100190 |
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| 基金项目： | 中国科学院知识创新工程青年人才领域项目 |
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| 摘 要： | 本文设计并实现了基于质谱的非标记定量软件QuantWiz,通过改变肽段定量的顺序,提高了定量软件的时间局部性和质谱数据缓存的命中次数。分析了QuantWiz的多种数据并行策略,设计并实现了按保留时间划分的并行定量软件P-QuantWiz。通过实验验证P-QuantWiz具有良好的并行效率,当进程数为32时,并行效率为63%。
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| 关 键 词： | 质谱 非标记定量 色谱峰 保留时间 并行化 |
P-QuantWiz: A Parallel Label-Free Quantification Software Based on Mass Spectrometry |
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| HU Ze-lin,ZHANG Yun-quan,WANG Jing,ZHANG Xian-yi.P-QuantWiz: A Parallel Label-Free Quantification Software Based on Mass Spectrometry[J].Computer Engineering & Science,2009,31(11). |
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| Authors: | HU Ze-lin ZHANG Yun-quan WANG Jing ZHANG Xian-yi |
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| Abstract: | A new label-free quantification software based on mass spectrometry, named QuantWiz, is designed and im-plemented in this paper. By changing the order of peptide quantification, the time locality and mass spectrometry data cache hits of QuantWiz are improved The data parallel strategies are also analyzed,and the parallel quantification software called P-QuantWiz based on retention time partitioning is designed and implemented. A lot of experiments show that the parallel-ism efficiency is very high, whenever the process number is 32, the parallelism efficiency is 63%. |
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| Keywords: | mass spectrometry label-free quantification chromatographic peaks retention time parallelization |
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