曲美他嗪对冠心病合并左心功能不全的效果

目的 探讨冠心病合并左心功能不全患者行曲美他嗪治疗的临床效果.方法 选择医院于2016年3月—2017年4月期间接收的老年冠心病合并左心功能不全患者60例,采用随机数字表法形式均分为研究组和对照组,每组均30例.对照组行基础治疗,研究组在此基础上口服曲美他嗪,记录两组心功能指标以及不良反应发生率.结果 研究组治疗后LVEDD、LVESD指标低于对照组,左心室射血分数高于对照组(P<0.05);研究组和对照组在用药过程中均未出现严重的反应,研究组出现3例转氨酶上升,2例胃肠道不适;对照组出现2例转氨酶上升,组间对比P<0.05.结论 曲美他嗪行冠心病合并左心功能不全治疗效果明显,心肌功能以及血脂水平有所改善.

Effect of Trimetazidine on Coronary Heart Disease Complicated With Left Ventricular Insufficiency

Objective To investigate the clinical effect of trimetazidine in patients with coronary heart disease complicated with left cardiac dysfunction.Methods 60 cases of elderly patients with coronary heart disease complicated with left ventricular dysfunction admitted to our hospital from March 2016 to April 2017 were selected and divided into study group and control group by random number table method,with 30 cases in each group.The control group received basic treatment,and the study group took oral trimetazidine on this basis,and recorded the cardiac function indicators and the incidence of adverse reactions in the two groups.Results After treatment,LVEDD and LVESD indexes in the study group were lower than those in the control group,and left ventricular ejection fraction was higher than that in the control group(P<0.05).Neither the study group nor the control group showed serious reactions during the course of medication.Conclusion Trimetazidine is effective in the treatment of coronary heart disease complicated with left cardiac insufficiency.