抗苗勒氏管激素在妇产科领域的研究进展

抗苗勒氏管激素(AMH)属于转化生长因子β超家族,在调节生殖细胞发育和分化中发挥重要作用,本文阐述了AMH与卵巢功能、多囊卵巢综合征(PCOS)、辅助生殖以及肿瘤的关系。研究显示血清AMH水平可以准确反映卵巢储备能力,在辅助生殖中具有重要应用价值,AMH还可以作为诊断多PCOS的指标。近年来越来越多的研究表明血清AMH升高是卵巢癌等肿瘤的标志物,且AMH对卵巢癌等肿瘤的生长、迁移和侵袭有抑制作用,可能成为肿瘤治疗的新药物。AMH在妇产科领域具有广阔的的应用前景。

Research Progress of Anti-Mullerian Hormone in the Field of Gynaecology and Obstetrics

Anti-Mullerian hormone （AMH） belongs to the family of TGF-beta growth factors, and it plays an important role in regulating the development and differentiation of reproduction cells. In this paper we stated the relationship between AMH with ovary function, polycystic ovary syndrome （PCOS）, assistant reproduction or tumor. Research indicated that AMH can accurately reflect ovary function, thus it has important practical value in the field of assistant reproduction, AMH also can be used for the marker of dignosing the PCOS. In latest years more and more researches indicated that serum AMH rise can act as the marker of tumor such as ovary cancer. Furthermore, AMH can inhibit growth, migration and invasion of tumor such as ovary cancer, which can be possibly used for the new drug of tumor curity. So AMH has a prosperous application in the field of gynaecology and obstetrics.