| HX-Ⅰ液作为腹部内多器官灌注液可行性研究 |
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| 引用本文： | 彭兵,张锐敏,王向东,沈文律,吴和光.HX-Ⅰ液作为腹部内多器官灌注液可行性研究[J].苏州大学学报(自然科学版),1999(5). |
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| 作者姓名： | 彭兵 张锐敏 王向东 沈文律 吴和光 |
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| 作者单位： | 华西医科大学附属一院普外科!610041 |
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| 摘 要： | 采用大鼠肝脏非循环离体灌注模型，观察HX-Ⅰ液对大鼠肝组织含水量、肝窦内皮细胞死亡率，Krebs－Henseleit液天门冬氨酸转移酶活性、分泌胆汁的肝脏数量;观察HX-Ⅰ液对糖尿病大鼠胰腺移植术后血糖（Pod＋2，7，14）、糖耐量、胰岛素变化；观察HX-Ⅰ液对狗肾移植术后血肌酐、存活率及肝、胰、肾脏的形态学。结果表明，HX-Ⅰ液保存大鼠肝脏达24h，胰腺48h，狗肾脏达72h。说明HX-Ⅰ液作为腹部内多器官灌注液是可行的。
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| 关 键 词： | HX-Ⅰ液 大鼠 肝 肾 胰 保存液 |
The Possible Study of HX - I Solution for All Intra - Abdominal Organs Preservation |
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| Peng Bing,et al.The Possible Study of HX - I Solution for All Intra - Abdominal Organs Preservation[J].Suzhou University Journal of Medical Science,1999(5). |
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| Authors: | Peng Bing |
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| Abstract: | The effectS of HX - I solution for all intraabdondnal organs preservation were studied with n0ncirculated isolated per-fused rat liver modeI, rat pancrease isogralls model on the diabetie rats, and kidney autotransplan:model. The effectswere inveated by measuring hepatic tissmater content, sinusoidal lining cell morta1ity, krehs - Hense1eits Perfusateaspartate andnotransferase. The number of livers secreting bile during i5olated perfusion, blo0d glucose. glucose tolerancetests and serum insalin of the rat pancreas - transplant recipients, and the maximum selllm creatinine, levels, kidneysgraf survival rates and by observing the morphological changes in liver, pancreas, kidneys. The experimental findings in-dicated that HX - I solution appears to be effective for preserving all intraabdominal organs and may simplify c0ld storageof organs for transplantation. |
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| Keywords: | intraabdominal organs HX - I Solution liver pancreas kidney |
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