| 微粒子捕捉酶免疫法检测肿瘤标志物CA19-9的临床应用 |
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| 引用本文： | 李永军,曹青,王丽芳,郭芳,郭欣,崔幸琨. 微粒子捕捉酶免疫法检测肿瘤标志物CA19-9的临床应用[J]. 河北医药, 2001, 23(10): 725-726 |
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| 作者姓名： | 李永军 曹青 王丽芳 郭芳 郭欣 崔幸琨 |
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| 作者单位： | 1. 050000,河北医科大学第二医院
2. 华北石油总医院检验科 |
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| 基金项目： | 河北省卫生厅资助项目 编号 980 0 2 1 1 |
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| 摘 要： | 目的：评价微粒子捕捉酶免疫法检测糖链抗原19－9（CA19－9）的临床应用价值。方法：运用微粒子捕捉酶免疫方法检测胃癌、肝癌、胰腺癌及胰腺炎、良性胃疾病患者和健康人的血清CA19－9水平。结果：胃癌、肝癌、胰腺癌患者的CA19－9水平较健康人显著升高，对胰腺癌及胃癌的正确诊断率分别为89．8％及93．4％。结论：CA19－9是诊断胰腺癌及胃癌的最为有效的肿瘤标志物之一，运用微粒子捕捉免疫技术进行检测可提高临床诊断水平。
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| 关 键 词： | 微粒子捕捉酶免疫方法 糖链抗原19－9 肿瘤标志物 消化道肿瘤 诊断 |
| 修稿时间： | 2001-03-21 |
Clinical study on the detection of carbohydrate antigen 19-9 by micropartical enzyme immunoassay |
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| LI Yongjun,CAO Qing,WANG Lifang,et al.. Clinical study on the detection of carbohydrate antigen 19-9 by micropartical enzyme immunoassay[J]. Hebei Medical Journal, 2001, 23(10): 725-726 |
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| Authors: | LI Yongjun CAO Qing WANG Lifang et al. |
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| Affiliation: | LI Yongjun,CAO Qing,WANG Lifang,et al.Second Hospital of Hebei Medical University,Shijiazhuang 050000 |
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| Abstract: | Objective To evaluate the clinical significance of the detection of carbohydrate antigen 19 9(CA19 9) by microparticle enzyme immunoassay (MEIA).Methods The serum levels of CA19 9 were assayed by MEIA in 45 gastric cancer patients,36 liver cancer patients,12 pancreatoncus patients,as well as healthy group.Results The levels of CA19 9 in groups of gastric cancer,liver cancer and pancreatoncus were significantly higher than that in healthy group.The rate of diagnostic coincidence was 89..8% in pancreatoncus and 93.4% in gastric cancer.Conclusion CA19 9 is one of the most effective tumor markers in diagnosing gastric cancer and pancreatoncus.The clinical diagnostic level can be improved by using MEIA. |
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| Keywords: | microparticle enzyme immunoassay carbohydrate antigen 19 9 |
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