女贞子化学成分与药理作用研究进展

综述近10年女贞子研究文献，为进一步合理研究开发女贞子提供参考。查阅近年来的75篇女贞子相关文献，按照化学成分、药理作用、炮制和质量控制4方面总结女贞子的研究现状。女贞子主要含有萜类、黄酮类、苯乙醇苷类、挥发油、磷脂、多糖、脂肪酸、氨基酸、微量元素等化学成分，主要具有保肝、免疫调节、抗动脉粥样硬化、抗炎、抗衰老等药理作用，目前对女贞子的炮制方法以酒蒸、酒炖、盐炙、醋蒸为主，不同炮制方法对药物的化学成分、药理作用均有影响，质量控制方法以薄层扫描法和高效液相色谱法为主。研究成果表明女贞子中的化学成分丰富，药理作用显著，特别是近年对于老年退行性病变的研究结果显示女贞子是极具开发前景的药食同源药材，有待于进一步开发。此外，对女贞子炮制、质量控制研究应兼顾不同极性成分。

Research Progress of Chemical Composition and Pharmacological Effects of Fructus Figustri Lucidi

Literature about Fructus Figustri Lucidi in the last decade was reviewed to provide a reference for further research and development. Seventy-five literatures were summarized according to chemical composition, pharmacological action, processing and quality control method. The main chemical components of Fructus Figustri Lucidi were terpenoids, flavonoids, phenethyl alcohol glycosides, volatile oils, phospholipids, polysaccharides, fatty acids, amino acids, and etc. It is reported that its main pharmacological effects were hepatoprotective, immune regulation, anti-atherosclerotic, anti-inflammatory, anti-aging, and etc. The main processing methods were steaming with wine, stewing with wine, stir-frying with salt-water, steaming with vinegar. Chemical composition and pharmacological effects were influenced by the processing method. TLC and HPLC were adopted as the main QC method. Fructus Figustri Lucidi was reported as one herbal tonic, which had significant pharmacological effects on degenerative disease, especially on the old. As one effective edible herbs, Fructus Figustri Lucidi should be studied comprehensively. In addition, ingredients of different polarity should all be taken into account in the further study.