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| NUCLEOLAR ORGANIZER REGIONS IN CUTANEOUS T CELL LYMPHOMAS | |
| 引用本文： | 许良中,陈红莉,邱丙森,陶玲娣. NUCLEOLAR ORGANIZER REGIONS IN CUTANEOUS T CELL LYMPHOMAS[J]. 中国癌症研究, 1990, 2(3): 58-61. DOI: 10.1007/BF02997234 |
| 作者姓名： | 许良中 陈红莉 邱丙森 陶玲娣 |
| 作者单位： | Department of Pathology，Cancer Hospital，Shanghai Medical University，Department of Pathology，Cancer Hospital，Shanghai Medical University，Laboratory of Dermatopathology，Huashan Hospital，Shanghai Medical University，Laboratory of Dermatopathology，Huashan Hospital，Shanghai Medical University |
| 摘 要： | The present work studied the application of AgNOR count to differential diagnosis between cutaneous T cell lymphoma (CTCL) and cutaneous pseudolymphoma (CPL). Paraffin sections from 50 mycosis fungoides (22 MFI-Premycotic stage, 24 MF Ⅰ infiltrative stage and 4 MF Ⅲ - tumor stage), 2 nonepidermotropic cutaneous T cell lymphoma (NECTCL) and 9 CPL were investigated. In each case, 200 cells randomly selected were examined using a × 100 oil immersion lens. The mean number, standard deviation and standard error of the mean of AgNOR counts were as follows: MFⅠ 1.17±0.09, SEM = 0.01; MⅡ 1.17±0.01, SEM = 0.01; MF Ⅲ. 3.55±0.87, SEM = 0.43; NECTCL 4.5±0.28, SEM -0.199; CPL 1.17±0.1, SEM ± 0.03. The results revealed a highly significant difference between CTCL (MFⅢ NECTCL) and CPL (t = 4.75, P<0.001), tumor stage (MF Ⅲ) and pretumor stage (MFI, MF Ⅱ) of mycosis fungoides (t = 4.75, P<0.001). Thus. AgNOR count is valuable in differential diagnosis. |
Nucleolar organizer regions in cutaneous T cell lymphomas |
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| Xu,Liangzhong,Chen,Hongli,Qiu,Bingsen,Tao,Lingdi. Nucleolar organizer regions in cutaneous T cell lymphomas[J]. Chinese Journal of Cancer Research, 1990, 2(3): 58-61. DOI: 10.1007/BF02997234 | |
| Authors: | Xu Liangzhong Chen Hongli Qiu Bingsen Tao Lingdi |
| Affiliation: | 1.Department of Pathology, Cancer Hospital, Shanghai Medical University, China ;2.Laboratory of Dermatopathology, Huashan Hospital, Shanghai Medical University, China ; |
| Abstract: | The present work studied the application of AgNOR count to differential diagnosis between cutaneous T cell lymphoma (CTCL) and cutaneous pseudolymphoma (CPL). Paraffin sections from 50 mycosis fungoides (22 MFI-Premycotic stage, 24 MF II infiltrative stage and 4 MF III — tumor stage), 2 nonepidermotropic cutaneous T cell lymphoma (NECTCL) and 9 CPL were investigated. In each case, 200 cells randomly selected were examined using a × 100 oil immersion lens. The mean number, standard deviation and standard error of the mean of AgNOR counts were as follows: MFI 1.17±0.09, SEM=0.01; MF II 1.17±0.01, SEM=0.01; MF III 3.55±0.87, SEM=0.43; NECTCL 4.5±0.28, SEM=0.199; CPL 1.17±0.1, SEM±0.03. The results revealed a highly significant difference between CTCL (MF III+NECTCL) and CPL (t=4.75,P<0.001), tumor stage (MF III) and pretumor stage (MFI, MF II) of mycosis fungoides (t=4.75,P<0.001). Thus. AgNOR count is valuable in differential diagnosis. |
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