AECOPD住院期间cTnT预后价值初探

目的评价cTnT在慢性阻塞性肺疾病急性加重期（AECOPD）住院期间的预后价值。方法采用前瞻性队列研究方法，测定82例AECOPD住院患者血清cTnT、Mb、CK-MBmass，收集患者临床资料，随访临床结局（死亡或存活）。采用单因素、Logistic回归分析进行预后分析。结果logistic多元回归分析结果显示，PaO2、cTnT增高、P（A-a）O2、年龄为AECOPD住院期间的主要预后因素（P〈0．05）。结论cTnT增高是AECOPD住院期间的主要预后指标。

A preliminary study on the prognostic value of cardiac tropinin T for in-hospital death in patients with acutely exacerbated chronic obstructive pulmonary disease

Objective To assess the prognostic value of cTnT elevation during hospital stay for acute exacerbation of chronic obstructive pulmonary disease. Methods Eighty-two consecutive patients with confirmed acute exacerbation of chronic obstructive pulmonary disease were enrolled in this prospective study. Serum cTnT,myoglobin(Mb),creatine kinase-MB mass(CK-MBmass)were measured and a variety of clinical and laboratory variables were collected,then followed up clinic outcome(death and survival). Univariate analysis and Logistic regression analysis was used to prognosis analysis. Results Age, PaO2, P(A-a)O2 and cTnT elevation was identified as principal predictors of in-hospital death in a logistic regression model. Conclusions Elevated cTnT is a principal prognostic factor of in-hospital death in patients admitted for acutely exacerbated chronic obstructive pulmonary disease.