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| 反相高效液相色谱梯度洗脱同时测定复方茶碱片中7组分的含量 | |
| 引用本文： | 王霞,刘道杰,孙吉令.反相高效液相色谱梯度洗脱同时测定复方茶碱片中7组分的含量[J].分析化学,2003,31(5):577-579. |
| 作者姓名： | 王霞 刘道杰 孙吉令 |
| 作者单位： | 1. 聊城大学化学系,聊城,252059;中国科学院兰州化学物理研究所,兰州,730000 2. 聊城大学化学系,聊城,252059 3. 山东省药品检验所,济南,250012 |
| 摘 要： | 建立了一种灵敏、快速的反相高效液相色谱梯度洗脱方法，用于同时测定复方茶碱片中7组分的含量。采用YWG C18柱，以甲醇-磷酸二氢钠为流动相，用二极管阵列检测器，检测波长为214nm,15min即可将7种组分分离测定。该方法快速淮确，线性范围广，用于实际样品的测定，结果满意。 |
| 关 键 词： | 反相高效液相色谱 梯度洗脱 同时测定 复方茶碱片 药物含量 平喘药 |
Simultaneous Determination of Seven Ingredients in compound Theophylline Tablets by Reversed Phase High Performance Liquid Chromatography Gradient Elution |
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| Wang Xia,Liu Daojie,Sun Jiling.Simultaneous Determination of Seven Ingredients in compound Theophylline Tablets by Reversed Phase High Performance Liquid Chromatography Gradient Elution[J].Chinese Journal of Analytical Chemistry,2003,31(5):577-579. | |
| Authors: | Wang Xia Liu Daojie Sun Jiling |
| Abstract: | A reversed phase high performance liquid chromatography ( RP-HPLC) gradient elution method was proposed for the simultaneous determination of seven active ingredients in compound theophylline tablets. A YWG C18 column and a binary mobile phase of methanol and sodium dihydrogen phosphate were used. A photo-diode array detector was used to detect the compositions with 214 nm as the detection wavelength. The whole process could be performed within 15 minutes. The proposed method was accurate and rapid with wide linear range and reliable results. It has been applied to assaying the real sample with satisfactory results. |
| Keywords: | Reversed phase high performance liquid chromatography gradient elution compound theophylline tablets |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |
