益肾温经祛湿法治疗强直性脊柱炎的临床观察

目的观察益肾温经祛湿法治疗肾虚寒凝型强直性脊柱炎的临床疗效。方法44例患者随机分为治疗组和对照组,治疗组采用益肾温经祛湿的中药协定方,对照组采用缓解病情的西药。疗程3个月。治疗前后评价Bath强脊功能指数(BASFI)、强脊疾病活动指数(BASDAI)、指地距、扩胸度、枕壁距、Schober试验、血沉、C-反应蛋白及血尿常规、肝肾功能。结果治疗后两组BASDAI、BASFI、C-反应蛋白均有显著性改善,治疗组BASFI改善优于对照组,治疗组治疗前后血沉、指地距变化有统计学意义(P<0.05),两组Schober试验、枕壁距、扩胸度变化均无统计学意义(P>0.05)。治疗组总有效率为76.2%,对照组为65.2%(P>0.05)。治疗组中医证候改善优于对照组。结论益肾温经祛湿法疗效较好。

Clinical Observation of Kidney-Nourishing, Meridian-Warming and Dampness-Removing Therapy for Ankylosing Spondylitis

Objective To observe the effect of method of nourishing kidney,warming meridian and removing dampness on ankylosing spondylitis.Methods 44 patients with AS were randomly allocated to two groups.In treatment group(n=21) decoction was carried on,and in control group(n=23) Disease-Modifying Anti-Rheumatic Drugs(DMARDs) was utilized,with a therapeutic course of three months.We observed effective rate,BASDAI,BASFI,C-reactive protein,ESR,the range of motion of the lumbar,such as Schober test,chest expansion.We also observed the symptoms of Traditional Chinese medicine.Results There was no statistically significant difference between treatment group and control group in the total effective rate.Conclusion method of nourishing kidney,warming meridian and removing dampness can control the activity of ankylosing spondylitis.