油酰柠檬酸三乙酯的合成及红外光谱研究

以柠檬酸和乙醇为原料,在磷酸和苯磺酸混合催化剂作用下,加热回流,酯化生成柠檬酸三乙酯。以油酸与氯化亚砜为原料,通过酰化反应合成油酰氯。再使柠檬酸三乙酯与油酰氯在吡啶作用下,通过酰基化反应合成油酰柠檬酸三乙酯。采用红外光谱法对原料、中间体、产物进行了红外光谱测试,并进行了红外谱图的分析与比较,证明了各步产品为目的产物。根据原料、中间体、产物红外谱图中相应特征吸收峰的消失或是出现,证明了所选择的合成工艺路线是可行的。

Synthesis and Spectral Characterization of Triethyl Oleoylcitrate

The triethyl citrate was esterified based on citric acid and alcohol with the catalysis of phosphoric acid and benzene sulfonic acid under reflux condition; oleoyl chloride was synthesizded from oleic acid and thionyl chloride through acylation reaction;and triethyl oleoylcitrate was synthesized from triethyl citrate and oleoyl chloride through acylation reaction by the action of pyridine. The materials,intermediates and products were tested by infrared spectroscopy,and each product was proved to be the objective outcome by the analysis and compared of the infrared spectrogram.The chosen synthetic technological route was proved to be feasible by the appearance or vanish of characteristic absorption peaks of the materials,intermediates and products.